Anesthesiology and Pain Medicine

Published by: Kowsar

Effect of Remote Ischemic Preconditioning on Troponin I in CABG

Fatemeh Javaherforoosh Zadeh 1 , Mohsen Moadeli 2 , * , Mansoor Soltanzadeh 3 and Farahzad Janatmakan 2
Authors Information
1 Associate Professor of Anesthesia, Department of Anesthesia, Ahvaz Anesthesiology and Pain Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
2 Assistant Professor of Anesthesia, Department of Anesthesia, Ahvaz Anesthesiology and Pain Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
3 Professor of Anesthesia, Department of Anesthesia, Ahvaz Anesthesiology and Pain Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
Article information
  • Anesthesiology and Pain Medicine: August 2017, 7 (4); e12549
  • Published Online: August 21, 2017
  • Article Type: Research Article
  • Received: April 4, 2017
  • Revised: May 4, 2017
  • Accepted: August 7, 2017
  • DOI: 10.5812/aapm.12549

To Cite: Javaherforoosh Zadeh F, Moadeli M, Soltanzadeh M, Janatmakan F. Effect of Remote Ischemic Preconditioning on Troponin I in CABG, Anesth Pain Med. 2017 ; 7(4):e12549. doi: 10.5812/aapm.12549.

Copyright © 2017, Anesthesiology and Pain Medicine. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License ( which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Background
2. Objectives
3. Methods
4. Results
5. Discussion
  • 1. Hoole SP, Heck PM, Sharples L, Khan SN, Duehmke R, Densem CG, et al. Cardiac Remote Ischemic Preconditioning in Coronary Stenting (CRISP Stent) Study: a prospective, randomized control trial. Circulation. 2009; 119(6): 820-7[DOI][PubMed]
  • 2. Kizer JR, Muttrej MR, Matthai WH, McConnell J, Nardone H, Sonel AF, et al. Role of cardiac troponin T in the long-term risk stratification of patients undergoing percutaneous coronary intervention. Eur Heart J. 2003; 24(14): 1314-22[PubMed]
  • 3. Lucchinetti E, Bestmann L, Feng J, Freidank H, Clanachan AS, Finegan BA, et al. Remote ischemic preconditioning applied during isoflurane inhalation provides no benefit to the myocardium of patients undergoing on-pump coronary artery bypass graft surgery: lack of synergy or evidence of antagonism in cardioprotection? Anesthesiology. 2012; 116(2): 296-310[DOI][PubMed]
  • 4. Lattouf OM, Thourani VH, Kilgo PD, Halkos ME, Baio KT, Myung R, et al. Influence of on-pump versus off-pump techniques and completeness of revascularization on long-term survival after coronary artery bypass. Ann Thorac Surg. 2008; 86(3): 797-805[DOI][PubMed]
  • 5. Hausenloy DJ, Candilio L, Evans R, Ariti C, Jenkins DP, Kolvekar S, et al. Remote Ischemic Preconditioning and Outcomes of Cardiac Surgery. N Engl J Med. 2015; 373(15): 1408-17[DOI][PubMed]
  • 6. Lomivorotov VV, Shmyrev VA, Nepomnyaschih VA, Ponomarev DN, Knyazkova LG, Lomivorotov VN, et al. Remote ischaemic preconditioning does not protect the heart in patients undergoing coronary artery bypass grafting. Interact Cardiovasc Thorac Surg. 2012; 15(1): 18-22[DOI][PubMed]
  • 7. Pell TJ, Baxter GF, Yellon DM, Drew GM. Renal ischemia preconditions myocardium: role of adenosine receptors and ATP-sensitive potassium channels. Am J Physiol. 1998; 275(5 Pt 2)-7[PubMed]
  • 8. Shimizu M, Tropak M, Diaz RJ, Suto F, Surendra H, Kuzmin E, et al. Transient limb ischaemia remotely preconditions through a humoral mechanism acting directly on the myocardium: evidence suggesting cross-species protection. Clin Sci (Lond). 2009; 117(5): 191-200[DOI][PubMed]
  • 9. Choi YS, Shim JK, Kim JC, Kang KS, Seo YH, Ahn KR, et al. Effect of remote ischemic preconditioning on renal dysfunction after complex valvular heart surgery: a randomized controlled trial. J Thorac Cardiovasc Surg. 2011; 142(1): 148-54[DOI][PubMed]
  • 10. Karuppasamy P, Chaubey S, Dew T, Musto R, Sherwood R, Desai J, et al. Remote intermittent ischemia before coronary artery bypass graft surgery: a strategy to reduce injury and inflammation? Basic Res Cardiol. 2011; 106(4): 511-9[DOI][PubMed]
  • 11. Hu S, Dong HL, Li YZ, Luo ZJ, Sun L, Yang QZ, et al. Effects of remote ischemic preconditioning on biochemical markers and neurologic outcomes in patients undergoing elective cervical decompression surgery: a prospective randomized controlled trial. J Neurosurg Anesthesiol. 2010; 22(1): 46-52[DOI][PubMed]
  • 12. D'ascenzo F, Cavallero E, Moretti C, Omede P. , Sciuto F, Rahman IA, et al. Remote ischaemic preconditioning in coronary artery bypass surgery: a meta-analysis. Heart. 2012; 98(17): 1267-71
  • 13. Abdul-Ghani S, Heesom KJ, Angelini GD, Suleiman MS. Cardiac phosphoproteomics during remote ischemic preconditioning: a role for the sarcomeric Z-disk proteins. Biomed Res Int. 2014; 2014: 767812[DOI][PubMed]
  • 14. Lee JH, Park YH, Byon HJ, Kim HS, Kim CS, Kim JT. Effect of remote ischaemic preconditioning on ischaemic-reperfusion injury in pulmonary hypertensive infants receiving ventricular septal defect repair. Br J Anaesth. 2012; 108(2): 223-8[DOI][PubMed]
  • 15. Oxman T, Arad M, Klein R, Avazov N, Rabinowitz B. Limb ischemia preconditions the heart against reperfusion tachyarrhythmia. Am J Physiol. 1997; 273(4 Pt 2)-12[PubMed]
  • 16. Porto I, Blackman DJ, Nicolson D, Niccoli G, Kahn FZ, Ormerod O, et al. What is the incidence of myocardial necrosis in elective patients discharged on the same day following percutaneous coronary intervention? Heart. 2004; 90(12): 1489-90[DOI][PubMed]
  • 17. Zhu SB, Liu Y, Zhu Y, Yin GL, Wang RP, Zhang Y, et al. Remote preconditioning, perconditioning, and postconditioning: a comparative study of their cardio-protective properties in rat models. Clinics (Sao Paulo). 2013; 68(2): 263-8[PubMed]
  • 18. Kloner RA. Clinical application of remote ischemic preconditioning. Circulation. 2009; 119(6): 776-8[DOI][PubMed]
  • 19. Li L, Li G, Yu C, Li Y. The role of remote ischemic preconditioning on postoperative kidney injury in patients undergoing cardiac and vascular interventions: a meta-analysis. J Cardiothorac Surg. 2013; 8: 43[DOI][PubMed]
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