Anesthesiology and Pain Medicine

Published by: Kowsar

Comparing the Effect of Adding Fentanyl, Sufentanil, and Placebo with Intrathecal Bupivacaine on Duration of Analgesia and Complications of Spinal Anesthesia in Patients Undergoing Cesarean Section

Farnoush Farzi 1 , Ali Mirmansouri 2 , * , Bahram Naderi Nabi 3 , Zahra Atrkar Roushan 4 , Samaneh Ghazanfar Tehran 5 , Mona Nematollahi Sani 6 , Soodabe Makhlooghi Azad 6 and Maryam Nemati 6
Authors Information
1 Associate Professor of Anesthesiology, Anesthesiology Research Center, Department of Anesthesiology, Alzahra Hospital, Guilan University of Medical Sciences (GUMS), Rasht, Iran
2 Associate Professor of Anesthesiology, Anesthesiology Research Center, Department of Anesthesiology, Heshmat Hospital, Guilan University of Medical Sciences (GUMS), Rasht, Iran
3 Associate Professor of Anesthesiology, Anesthesiology Research Center, Department of Anesthesiology, Poursina Hospital, Guilan University of Medical Sciences (GUMS), Rasht, Iran
4 Assistant Professor of Statistics, Department of Statistics, Guilan University of Medical Sciences (GUMS), Rasht, Iran
5 Assistant Professor of Anesthesiology, Anesthesiology Research Center, Department of Anesthesiology, Alzahra Hospital, Guilan University of Medical Sciences (GUMS), Rasht, Iran
6 Resident of Anesthesia, Anesthesiology Research Center, Guilan University of Medical Sciences (GUMS), Rasht, Iran
Article information
  • Anesthesiology and Pain Medicine: October 2017, 7 (5); e12738
  • Published Online: August 27, 2017
  • Article Type: Research Article
  • Received: January 16, 2017
  • Revised: May 7, 2017
  • Accepted: August 7, 2017
  • DOI: 10.5812/aapm.12738

To Cite: Farzi F, Mirmansouri A, Naderi Nabi B, Atrkar Roushan Z, Ghazanfar Tehran S, et al. Comparing the Effect of Adding Fentanyl, Sufentanil, and Placebo with Intrathecal Bupivacaine on Duration of Analgesia and Complications of Spinal Anesthesia in Patients Undergoing Cesarean Section, Anesth Pain Med. 2017 ;7(5):e12738. doi: 10.5812/aapm.12738.

Abstract
Copyright © 2017, Anesthesiology and Pain Medicine. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Background
2. Objectives
3. Methods
4. Results
5. Discussion
Acknowledgements
Footnotes
References
  • 1. Horsager R, Roberts S, Rogers V, Santiago-Mu-oz P, Worley K, Hoffman B. Williams Obstetrics, Study Guide. 2014; : 587-609
  • 2. Braga AA, Frias JA, Braga FS, Poterio GB, Hirata ES, Torres NA. Spinal anesthesia for cesarean section. Use of hyperbaric bupivacaine (10mg) combined with different adjuvants. Rev Bras Anestesiol. 2012; 62(6): 775-87[DOI][PubMed]
  • 3. Gajbhare MKN, Kamble NP. Comparative study of intrathecal bupivacaine versus bupivacaine with fentanyl for cesarean section. India J Clin Anesth. 2016; 3(2): 271-7[DOI]
  • 4. Hunt CO, Naulty JS, Bader AM, Hauch MA, Vartikar JV, Datta S, et al. Perioperative analgesia with subarachnoid fentanyl-bupivacaine for cesarean delivery. Anesthesiology. 1989; 71(4): 535-40[DOI][PubMed]
  • 5. Venkata HG, Pasupuleti S, Pabba UG, Porika S, Talari G. A randomized controlled prospective study comparing a low dose bupivacaine and fentanyl mixture to a conventional dose of hyperbaric bupivacaine for cesarean section. Saudi J Anaesth. 2015; 9(2): 122-7[DOI][PubMed]
  • 6. Yahya M, Sriramamurthy K, Farhat S, Kumari S. Effect of addiction of fentanyl to low dose bupivacaine in cesarean under spinal anesthesia. Eur J Pharm Med Res. 2017; 4(2): 568-72
  • 7. Vyas N, Sahu DK, Parampill R. Comparative study of intrathecal sufentanil bupivacaine versus intrathecal bupivacaine in patients undergoing elective cesarean section. J Anaesthesiol Clin Pharmacol. 2010; 26(4): 488-92[PubMed]
  • 8. Yasuda SU, Zhang L, Huang SM. The role of ethnicity in variability in response to drugs: focus on clinical pharmacology studies. Clin Pharmacol Ther. 2008; 84(3): 417-23[DOI][PubMed]
  • 9. Hassani V, Movassaghi G, Safaian R, Safari S, Zamani MM, Hajiashrafi M, et al. Bupivacaine-sufentanil versus bupivacaine-fentanyl in spinal anesthesia of patients undergoing lower extremity surgery. Anesth Pain Med. 2014; 4(2)[DOI][PubMed]
  • 10. Nesionpoor SH, Javaherforosh F, Pipel Zadeh MR, Dehdashty A. Comparison of intrathecal fentanyl and sufentanil combined with lidocaine in elective Cesarean section [In Persion]. Sci Info Database. 2009; : 1-9
  • 11. Ousley R, Egan C, Dowling K, Cyna AM. Assessment of block height for satisfactory spinal anaesthesia for caesarean section. Anaesthesia. 2012; 67(12): 1356-63[DOI][PubMed]
  • 12. Chung CJ, Yun SH, Hwang GB, Park JS, Chin YJ. Intrathecal fentanyl added to hyperbaric ropivacaine for cesarean delivery. Reg Anesth Pain Med. 2002; 27(6): 600-3[DOI][PubMed]
  • 13. Huskisson EC. Pain measurment amd assessment. 1983; : 33-7
  • 14. Liu LL, Gropper MA. Postoperative analgesia and sedation in the adult intensive care unit: a guide to drug selection. Drugs. 2003; 63(8): 755-67[DOI][PubMed]
  • 15. Nasr IA, Elokda SA. Safety and efficacy of intrathecal adjuvants for cesarean section: bupivacaine, sufentanil, or dexmedetomidine. Ain-Shams J Anaesthesiol. 2015; 8(3): 388[DOI]
  • 16. Banihashem N, Hasannasab B, Esmaeili A, Hasannasab B. Addition of Intrathecal Magnesium Sulfate to Bupivacaine for Spinal Anesthesia in Cesarean Section. Anesth Pain Med. 2015; 5(3)[DOI][PubMed]
  • 17. Boules ML, Botros JM. Comparative study between the effect of intrathecal midazolam versus intrathecal midazolam plus magnesium sulfate on the efficacy and duration of analgesia in patients undergoing cesarean section. Ain-Shams J Anaesth. 2015; 8(1): 70[DOI]
  • 18. Faiz SH, Rahimzadeh P, Sakhaei M, Imani F, Derakhshan P. Anesthetic effects of adding intrathecal neostigmine or magnesium sulphate to bupivacaine in patients under lower extremities surgeries. J Res Med Sci. 2012; 17(10): 918-22[PubMed]
  • 19. Farzi F, Mirmansouri A, Forghanparast K, Heydarzadeh A, Abdollahzadeh M, Jahanyar Moghadam F. Addition of intrathecal fentanyl or meperidine to lidocaine and epinephrine for spinal anesthesia in elective cesarean delivery. Anesth Pain Med. 2014; 4(1)[DOI][PubMed]
  • 20. Sedighinejad A, Haghighi M, Naderi Nabi B, Rahimzadeh P, Mirbolook A, Mardani-Kivi M, et al. Magnesium sulfate and sufentanil for patient-controlled analgesia in orthopedic surgery. Anesth Pain Med. 2014; 4(1)[DOI][PubMed]
  • 21. Braga Ade F, Braga FS, Hirata ES, Pereira RI, Frias JA, Antunes IF. Association of lipophilic opioids and hyperbaric bupivacaine in spinal anesthesia for elective cesarean section. Randomized controlled study. Acta Cir Bras. 2014; 29(11): 752-8[DOI][PubMed]
  • 22. Thornton P, Hanumanthaiah D, O'Leary RA, Iohom G. Effects of fentanyl added to a mixture of intrathecal bupivacaine and morphine for spinal anaesthesia in elective caesearean section. Romanian J Anaesth Intens Care. 2015; 22(2): 97-102
  • 23. Goyal A, Shankaranarayan P, Ganapathi P. A randomized clinical study comparing spinal anesthesia with isobaric levobupivacaine with fentanyl and hyperbaric bupivacaine with fentanyl in elective cesarean sections. Anesth Essays Res. 2015; 9(1): 57-62[DOI][PubMed]
  • 24. Sarawat N, Mishra A, Chand T, Saxena S, Khan I, Saurabh G. comparative evaluation between intrathecal sufentanyl with bupivacaine to fentanyle with bupivacaine and bupivacaine aline for intraoperative and postoperative analgesia in infraumblical surgeires. Internet J Anesth. 2008; 19(2): 1-6
  • 25. Neeta S, Upadya M, Gosain A, Manissery JJ. A prospective randomized controlled study comparing intrathecal bupivacaine combined with fentanyl and sufentanil in abdominal and lower limb surgeries. Anesth Essays Res. 2015; 9(2): 149-54[DOI][PubMed]
  • 26. Motiani P, Chaudhary S, Bahl N, Sethi AK. Intrathecal sufentanil versus fentanyl for lower limb surgeries - a randomized controlled trial. J Anaesthesiol Clin Pharmacol. 2011; 27(1): 67-73[PubMed]
  • 27. Kim SY, Cho JE, Hong JY, Koo BN, Kim JM, Kil HK. Comparison of intrathecal fentanyl and sufentanil in low-dose dilute bupivacaine spinal anaesthesia for transurethral prostatectomy. Br J Anaesth. 2009; 103(5): 750-4[DOI][PubMed]
  • 28. Karbasy SH, Derakhshan P. Effects of opium addiction on level of sensory block in spinal anesthesia with bupivacaine for lower abdomen and limb surgery: a case-control study. Anesth Pain Med. 2014; 4(5)[DOI][PubMed]
  • 29. Khara BN, Rupera KB. Intrathecal sufentanil along with bupivacaine prolongs postoperative analgesia as compared to fentanyl with bupivacaine: A randomized trial. National J Med Res. 2013; 3(3): 229-32
  • 30. Li B, Wang H, Gao C. Bupivacaine in combination with fentanyl or sufentanil in epidural/intrathecal analgesia for labor: a meta-analysis. J Clin Pharmacol. 2015; 55(5): 584-91[DOI][PubMed]
  • 31. Dourado AD, Filho RL, Fernandes RA, Gondim MC, Nogueira EV. Sufentanil in combination with low-dose hyperbaric bupivacaine in spinal anesthesia for cesarean section: a randomized clinical trial. Braz J Anesthesiol. 2016; 66(6): 622-7[DOI][PubMed]
  • 32. Lee JH, Chung KH, Lee JY, Chun DH, Yang HJ, Ko TK, et al. Comparison of fentanyl and sufentanil added to 0.5% hyperbaric bupivacaine for spinal anesthesia in patients undergoing cesarean section. Korean J Anesthesiol. 2011; 60(2): 103-8[DOI][PubMed]
  • 33. Vandana T, Amit JI. A comparative clinical study of intrathecal fentanyl v/s sufentanil with bupivacaine for postoperative analgesia in emergency or elective Cesarean section. Indian J Pain. 2008; 22(157-62)
  • 34. Onk D, Akarsu Ayazoglu T, Kuyrukluyildiz U, Aksut M, Bedir Z, Kupeli I, et al. Effects of Fentanyl and Morphine on Shivering During Spinal Anesthesia in Patients Undergoing Endovenous Ablation of Varicose Veins. Med Sci Monit. 2016; 22: 469-73[DOI][PubMed]
  • 35. Faiz SH, Rahimzadeh P, Imani F, Bakhtiari A. Intrathecal injection of magnesium sulfate: shivering prevention during cesarean section: a randomized, double-blinded, controlled study. Korean J Anesthesiol. 2013; 65(4): 293-8[DOI][PubMed]
  • 36. Agrawal A, Agrawal S, Asthana V, Payal Y, Sharma J, Gupta V. Comparison of intrathecal fentanyl and Sufentanil in addition to bupivacaine for caesarean section under spinal anaesthesia. J Anaesth Cli Pharma. 2009; 25(2): 154
  • 37. Karbasy SH, Derakhshan P. The effect of low dose fentanyl as a premedication before induction of general anesthesia on the neonatal apgar score in cesarean section delivery: randomized, double-blind controlled trial. Med J Islam Repub Iran. 2016; 30: 361[PubMed]
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