Anesthesiology and Pain Medicine

Published by: Kowsar

Effect of Dexmedetomidine Versus Nalbuphine as an Adjuvant on Paravertebral Block to Manage Postoperative Pain After Mastectomies

Mohammad Omar Mostafa 1 , Joseph Makram Botros 1 , * and Atef Mohammad Sayed Khaleel 1
Authors Information
1 Anesthesiology, Faculty of Medicine, Fayoum University, Faiyum, Egypt
Article information
  • Anesthesiology and Pain Medicine: April 2018, 8 (2); e13308
  • Published Online: April 28, 2018
  • Article Type: Research Article
  • Received: May 14, 2017
  • Revised: March 27, 2018
  • Accepted: March 29, 2018
  • DOI: 10.5812/aapm.13308

To Cite: Omar Mostafa M, Makram Botros J, Sayed Khaleel A M. Effect of Dexmedetomidine Versus Nalbuphine as an Adjuvant on Paravertebral Block to Manage Postoperative Pain After Mastectomies, Anesth Pain Med. 2018 ; 8(2):e13308. doi: 10.5812/aapm.13308.

Abstract
Copyright © 2018, Anesthesiology and Pain Medicine. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited
1. Background
2. Methods
3. Results
4. Discussion
References
  • 1. Smith RA, Cokkinides V, Brawley OW. Cancer screening in the United States, 2009: a review of current American Cancer Society guidelines and issues in cancer screening. CA Cancer J Clin. 2009;59(1):27-41. doi: 10.3322/caac.20008. [PubMed: 19147867].
  • 2. Poleshuck EL, Katz J, Andrus CH, Hogan LA, Jung BF, Kulick DI, et al. Risk factors for chronic pain following breast cancer surgery: a prospective study. J Pain. 2006;7(9):626-34. doi: 10.1016/j.jpain.2006.02.007. [PubMed: 16942948].
  • 3. Imani F. Postoperative pain management. Anesth Pain Med. 2011;1(1):6-7. doi: 10.5812/kowsar.22287523.1810. [PubMed: 25729647]. [PubMed Central: PMC4335751].
  • 4. Hemati K, Zaman B, Hassani V, Imani F, Dariaie P. Efficacy of fentanyl transdermal patch in the treatment of chronic soft tissue cancer pain. Anesth Pain Med. 2015;5(1). e22900. doi: 10.5812/aapm.22900. [PubMed: 25789240]. [PubMed Central: PMC4350185].
  • 5. Mohamed SA, Fares KM, Mohamed AA, Alieldin NH. Dexmedetomidine as an adjunctive analgesic with bupivacaine in paravertebral analgesia for breast cancer surgery. Pain Physician. 2014;17(5):E589-98. [PubMed: 25247908].
  • 6. Bajwa SJ, Arora V, Kaur J, Singh A, Parmar SS. Comparative evaluation of dexmedetomidine and fentanyl for epidural analgesia in lower limb orthopedic surgeries. Saudi J Anaesth. 2011;5(4):365-70. doi: 10.4103/1658-354X.87264. [PubMed: 22144922]. [PubMed Central: PMC3227304].
  • 7. El-Hennawy AM, Abd-Elwahab AM, Abd-Elmaksoud AM, El-Ozairy HS, Boulis SR. Addition of clonidine or dexmedetomidine to bupivacaine prolongs caudal analgesia in children. Br J Anaesth. 2009;103(2):268-74. doi: 10.1093/bja/aep159. [PubMed: 19541679].
  • 8. Gupta R, Bogra J, Verma R, Kohli M, Kushwaha JK, Kumar S. Dexmedetomidine as an intrathecal adjuvant for postoperative analgesia. Indian J Anaesth. 2011;55(4):347-51. doi: 10.4103/0019-5049.84841. [PubMed: 22013249]. [PubMed Central: PMC3190507].
  • 9. Gupta R, Verma R, Bogra J, Kohli M, Raman R, Kushwaha JK. A Comparative study of intrathecal dexmedetomidine and fentanyl as adjuvants to Bupivacaine. J Anaesthesiol Clin Pharmacol. 2011;27(3):339-43. doi: 10.4103/0970-9185.83678. [PubMed: 21897504]. [PubMed Central: PMC3161458].
  • 10. Sinha S, Mukherjee M, Chatterjee S, Vijay MK, Hazra A, Ray M. Comparative study of analgesic efficacy of ropivacaine with ropivacaine plus dexmedetomidine for paravertebral block in unilateral renal surgery. Anaesth Pain Intens Care. 2012;16:38-42.
  • 11. Fritsch G, Danninger T, Allerberger K, Tsodikov A, Felder TK, Kapeller M, et al. Dexmedetomidine added to ropivacaine extends the duration of interscalene brachial plexus blocks for elective shoulder surgery when compared with ropivacaine alone: a single-center, prospective, triple-blind, randomized controlled trial. Reg Anesth Pain Med. 2014;39(1):37-47. doi: 10.1097/AAP.0000000000000033. [PubMed: 24317234].
  • 12. Marhofer D, Kettner SC, Marhofer P, Pils S, Weber M, Zeitlinger M. Dexmedetomidine as an adjuvant to ropivacaine prolongs peripheral nerve block: a volunteer study. Br J Anaesth. 2013;110(3):438-42. doi: 10.1093/bja/aes400. [PubMed: 23161360].
  • 13. Obayah GM, Refaie A, Aboushanab O, Ibraheem N, Abdelazees M. Addition of dexmedetomidine to bupivacaine for greater palatine nerve block prolongs postoperative analgesia after cleft palate repair. Eur J Anaesthesiol. 2010;27(3):280-4. doi: 10.1097/EJA.0b013e3283347c15. [PubMed: 19935071].
  • 14. Chatrath V, Attri JP, Bala A, Khetarpal R, Ahuja D, Kaur S. Epidural nalbuphine for postoperative analgesia in orthopedic surgery. Anesth Essays Res. 2015;9(3):326-30. doi: 10.4103/0259-1162.158004. [PubMed: 26712968]. [PubMed Central: PMC4683471].
  • 15. Eid HEA. Paravertebral block: An overview. Curr Anaesth Crit Care. 2009;20(2):65-70.
  • 16. Eason MJ, Wyatt R. Paravertebral thoracic block-a reappraisal. Anaesthesia. 1979;34(7):638-42. [PubMed: 517716].
  • 17. Hui Yun S, Suk Choi Y. The Effects of Dexmedetomidine Administration on Postoperative Blood Glucose Levels in Diabetes Mellitus Patients Undergoing Spinal Anesthesia: A Pilot Study. Anesth Pain Med. 2016;6(6). e40483. doi: 10.5812/aapm.40483. [PubMed: 28975077]. [PubMed Central: PMC5560631].
  • 18. Guo TZ, Jiang JY, Buttermann AE, Maze M. Dexmedetomidine injection into the locus ceruleus produces antinociception. Anesthesiology. 1996;84(4):873-81. [PubMed: 8638842].
  • 19. Nelson LE, You T, Maze M, Franks NP. Evidence that the mechanism of hypnotic action in dexmedetomidine and muscimol-induced anesthesia converges on the endogenous sleep pathway. Anesthesiology. 2001;95. A1368.
  • 20. Amin SM, Amr YM, Fathy SM, Alzeftawy AE. Maternal and neonatal effects of nalbuphine given immediately before induction of general anesthesia for elective cesarean section. Saudi J Anaesth. 2011;5(4):371-5. doi: 10.4103/1658-354X.87265. [PubMed: 22144923]. [PubMed Central: PMC3227305].
  • 21. Cohen RI, Edwards WT, Kezer EA, Ferrari DA, Liland AE, Smith ER. Serial intravenous doses of dezocine, morphine, and nalbuphine in the management of postoperative pain for outpatients. Anesth Analg. 1993;77(3):533-9. [PubMed: 8368552].
  • 22. Acharya R, Jena M, Mishra S, Rath SK. Effect of butorphanol versus placebo as adjuvant to bupivacaine for supraclavicular brachial plexus blockade. Int J Appl Pharm. 2014;6(1):8-10.
  • 23. Moawad HE, Mousa SA, El-Hefnawy AS. Single-dose paravertebral blockade versus epidural blockade for pain relief after open renal surgery: A prospective randomized study. Saudi J Anaesth. 2013;7(1):61-7. doi: 10.4103/1658-354X.109814. [PubMed: 23717235]. [PubMed Central: PMC3657929].
  • 24. Moller JF, Nikolajsen L, Rodt SA, Ronning H, Carlsson PS. Thoracic paravertebral block for breast cancer surgery: a randomized double-blind study. Anesth Analg. 2007;105(6):1848-51. table of contents. doi: 10.1213/01.ane.0000286135.21333.fd. [PubMed: 18042892].
  • 25. Mohta M, Kalra B, Sethi AK, Kaur N. Efficacy of dexmedetomidine as an adjuvant in paravertebral block in breast cancer surgery. J Anesth. 2016;30(2):252-60. doi: 10.1007/s00540-015-2123-8. [PubMed: 26694929].
  • 26. Shaikh SI, Mahesh SB. The efficacy and safety of epidural dexmedetomidine and clonidine with bupivacaine in patients undergoing lower limb orthopedic surgeries. J Anaesthesiol Clin Pharmacol. 2016;32(2):203-9. doi: 10.4103/0970-9185.182104. [PubMed: 27275050]. [PubMed Central: PMC4874075].
  • 27. Gupta K, Jain M, Gupta PK, Rastogi B, Zuberi A, Pandey MN. Nalbuphine as an adjuvant to 0.5% bupivacaine for ultrasound-guided supraclavicular brachial plexus blockade. Indian J Pain. 2016;30(3):176. doi: 10.4103/0970-5333.198024.
  • 28. Abdelhaq MM, Adly Elramely M. Effect of Nalbuphine as Adjuvant to Bupivacaine for Ultrasound-Guided Supraclavicular Brachial Plexus Block. Open J Anesthesiol. 2016;6(3):20-6. doi: 10.4236/ojanes.2016.63004.
  • 29. Das A, RoyBasunia S, Mukherjee A, Biswas H, Biswas R, Mitra T, et al. Perineural Nalbuphine in Ambulatory Upper Limb Surgery: A Comparison of Effects of Levobupivacaine with and without Nalbuphine as Adjuvant in Supraclavicular Brachial Plexus Block - A Prospective, Double-blinded, Randomized Controlled Study. Anesth Essays Res. 2017;11(1):40-6. doi: 10.4103/0259-1162.200225. [PubMed: 28298754]. [PubMed Central: PMC5341634].
  • 30. Ammar AS, Mahmoud KM. Effect of adding dexamethasone to bupivacaine on transversus abdominis plane block for abdominal hysterectomy: A prospective randomized controlled trial. Saudi J Anaesth. 2012;6(3):229-33. doi: 10.4103/1658-354X.101213. [PubMed: 23162395]. [PubMed Central: PMC3498660].
  • 31. Abdallah FW, Brull R. Facilitatory effects of perineural dexmedetomidine on neuraxial and peripheral nerve block: a systematic review and meta-analysis. Br J Anaesth. 2013;110(6):915-25. doi: 10.1093/bja/aet066. [PubMed: 23587874].
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