Anesthesiology and Pain Medicine

Published by: Kowsar

Analgesic Effects of Intravenous Ketamine during Spinal Anesthesia in Pregnant Women Undergone Caesarean Section; A Randomized Clinical Trial

Shekoufeh Behdad 1 , Mohammad Reza Hajiesmaeili 2 , * , Hamid Reza Abbasi 1 , Vida Ayatollahi 1 , Zahra khadiv 3 and Alireza Sedaghat 2
Authors Information
1 Department of Anesthesiology, Shahid Sadoughi Hospital, Shahid Sadoughi University of Medical Sciences and Health Services, Yazd, Iran
2 Department of Anesthesiology and Critical Care Medicine, Rasoul Akram Medical Center, Iran University of medical sciences (IUMS), Tehran, Iran
3 Pain Research Center, Shahid Sadoughi University of Medical Sciences and Health Services, Yazd, Iran
Article information
  • Anesthesiology and Pain Medicine: September 26, 2013, 3 (2); 230-3
  • Published Online: September 1, 2013
  • Article Type: Research Article
  • Received: July 7, 2012
  • Revised: October 11, 2012
  • Accepted: June 20, 2013
  • DOI: 10.5812/aapm.7034

To Cite: Behdad S, Hajiesmaeili M R, Abbasi H R, Ayatollahi V, khadiv Z, et al. Analgesic Effects of Intravenous Ketamine during Spinal Anesthesia in Pregnant Women Undergone Caesarean Section; A Randomized Clinical Trial, Anesth Pain Med. 2013 ; 3(2):230-3. doi: 10.5812/aapm.7034.

Abstract
Copyright © 2013, Iranian Society of Regional Anesthesia and Pain Medicine (ISRAPM). This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Background
2. Objectives
3. Patients and Methods
4. Results
5. Discussion
Acknowledgements
Footnotes
References
  • 1. Yost NP, Bloom SL, Sibley MK, Lo JY, McIntire DD, Leveno KJ. A hospital-sponsored quality improvement study of pain management after cesarean delivery. Am J Obstet Gynecol. 2004; 190(5): 1341-6[DOI][PubMed]
  • 2. Bar-Oz B, Bulkowstein M, Benyamini L, Greenberg R, Soriano I, Zimmerman D, et al. Use of antibiotic and analgesic drugs during lactation. Drug Saf. 2003; 26(13): 925-35[PubMed]
  • 3. Wittels B, Glosten B, Faure EA, Moawad AH, Ismail M, Hibbard J, et al. Postcesarean analgesia with both epidural morphine and intravenous patient-controlled analgesia: neurobehavioral outcomes among nursing neonates. Anesth Analg. 1997; 85(3): 600-6[PubMed]
  • 4. Bell RF, Dahl JB, Moore RA, Kalso E. Perioperative ketamine for acute postoperative pain. Cochrane Database Syst Rev. 2006; (1)[DOI][PubMed]
  • 5. Mao J, Price DD, Mayer DJ. Mechanisms of hyperalgesia and morphine tolerance: a current view of their possible interactions. Pain. 1995; 62(3): 259-74[PubMed]
  • 6. Kashefi P. The benefits of intraoperative small-dose ketamine on postoperative pain after cesarean section. Anesthesiology. 2006; 104: 27
  • 7. Sen S, Ozmert G, Aydin ON, Baran N, Caliskan E. The persisting analgesic effect of low-dose intravenous ketamine after spinal anaesthesia for caesarean section. Eur J Anaesthesiol. 2005; 22(7): 518-23[PubMed]
  • 8. DeLoach LJ, Higgins MS, Caplan AB, Stiff JL. The visual analog scale in the immediate postoperative period: intrasubject variability and correlation with a numeric scale. Anesth Analg. 1998; 86(1): 102-6[PubMed]
  • 9. Burstal R, Danjoux G, Hayes C, Lantry G. PCA ketamine and morphine after abdominal hysterectomy. Anaesth Intensive Care. 2001; 29(3): 246-51[PubMed]
  • 10. Hercock T, Gillham MJ, Sleigh J, Jones SF. The addition of ketamine to patient controlled morphine analgesia does not improve quality of analgesia after total abdominal hysterectomy. Acute Pain. 1999; 2(2): 68-72
  • 11. Murdoch CJ, Crooks BA, Miller CD. Effect of the addition of ketamine to morphine in patient-controlled analgesia. Anaesthesia. 2002; 57(5): 484-8[PubMed]
  • 12. Unlugenc H, Ozalevli M, Guler T, Isik G. Postoperative pain management with intravenous patient-controlled morphine: comparison of the effect of adding magnesium or ketamine. Eur J Anaesthesiol. 2003; 20(5): 416-21[PubMed]
  • 13. Guillou N, Tanguy M, Seguin P, Branger B, Campion JP, Malledant Y. The effects of small-dose ketamine on morphine consumption in surgical intensive care unit patients after major abdominal surgery. Anesth Analg. 2003; 97(3): 843-7[PubMed]
  • 14. Heinke W, Grimm D. [Preemptive effects caused by co-analgesia with ketamine in gynecological laparotomies?]. Anaesthesiol Reanim. 1999; 24(3): 60-4[PubMed]
  • 15. Jaksch W, Lang S, Reichhalter R, Raab G, Dann K, Fitzal S. Perioperative small-dose S(+)-ketamine has no incremental beneficial effects on postoperative pain when standard-practice opioid infusions are used. Anesth Analg. 2002; 94(4): 981-6[PubMed]
  • 16. Aida S, Yamakura T, Baba H, Taga K, Fukuda S, Shimoji K. Preemptive analgesia by intravenous low-dose ketamine and epidural morphine in gastrectomy: a randomized double-blind study. Anesthesiology. 2000; 92(6): 1624-30[PubMed]
  • 17. De Kock M, Lavand'homme P, Waterloos H. 'Balanced analgesia' in the perioperative period: is there a place for ketamine? Pain. 2001; 92(3): 373-80[PubMed]
  • 18. Kararmaz A, Kaya S, Karaman H, Turhanoglu S, Ozyilmaz MA. Intraoperative intravenous ketamine in combination with epidural analgesia: postoperative analgesia after renal surgery. Anesth Analg. 2003; 97(4): 1092-6[PubMed]
  • 19. Dahl V, Ernoe PE, Steen T, Raeder JC, White PF. Does ketamine have preemptive effects in women undergoing abdominal hysterectomy procedures? Anesth Analg. 2000; 90(6): 1419-22[PubMed]
  • 20. Menigaux C, Fletcher D, Dupont X, Guignard B, Guirimand F, Chauvin M. The benefits of intraoperative small-dose ketamine on postoperative pain after anterior cruciate ligament repair. Anesth Analg. 2000; 90(1): 129-35[PubMed]
  • 21. Xie H, Wang X, Liu G, Wang G. Analgesic effects and pharmacokinetics of a low dose of ketamine preoperatively administered epidurally or intravenously. Clin J Pain. 2003; 19(5): 317-22[PubMed]
  • 22. Subramaniam B, Subramaniam K, Pawar DK, Sennaraj B. Preoperative epidural ketamine in combination with morphine does not have a clinically relevant intra- and postoperative opioid-sparing effect. Anesth Analg. 2001; 93(5): 1321-6[PubMed]
  • 23. Elhakim M, Khalafallah Z, El-Fattah HA, Farouk S, Khattab A. Ketamine reduces swallowing-evoked pain after paediatric tonsillectomy. Acta Anaesthesiol Scand. 2003; 47(5): 604-9[PubMed]
  • 24. O'Flaherty JE, Lin CX. Does ketamine or magnesium affect posttonsillectomy pain in children? Paediatr Anaesth. 2003; 13(5): 413-21[PubMed]
  • 25. Kwok RF, Lim J, Chan MT, Gin T, Chiu WK. Preoperative ketamine improves postoperative analgesia after gynecologic laparoscopic surgery. Anesth Analg. 2004; 98(4): 1044-9[PubMed]
  • 26. Menigaux C, Guignard B, Fletcher D, Sessler DI, Dupont X, Chauvin M. Intraoperative small-dose ketamine enhances analgesia after outpatient knee arthroscopy. Anesth Analg. 2001; 93(3): 606-12[PubMed]
  • 27. Loos MJ, Scheltinga MR, Mulders LG, Roumen RM. The Pfannenstiel incision as a source of chronic pain. Obstet Gynecol. 2008; 111(4): 839-46[DOI][PubMed]
  • 28. Nikolajsen L, Sorensen HC, Jensen TS, Kehlet H. Chronic pain following Caesarean section. Acta Anaesthesiol Scand. 2004; 48(1): 111-6[PubMed]
  • 29. Subramaniam K, Subramaniam B, Steinbrook RA. Ketamine as adjuvant analgesic to opioids: a quantitative and qualitative systematic review. Anesth Analg. 2004; 99(2): 482-95[DOI][PubMed]
  • 30. Meer FM, Downing JW, Coleman AJ. An intravenous method of anaesthesia for Caesarean section. II. Ketamine. Br J Anaesth. 1973; 45(2): 191-6[PubMed]
Creative Commons License Except where otherwise noted, this work is licensed under Creative Commons Attribution Non Commercial 4.0 International License .

Search Relations:

Author(s):

Article(s):

Create Citiation Alert
via Google Reader

Readers' Comments