Anesthesiology and Pain Medicine

Published by: Kowsar

Addition of Intrathecal Fentanyl or Meperidine to Lidocaine and Epinephrine for Spinal Anesthesia in Elective Cesarean Delivery

Farnoush Farzi 1 , Ali Mirmansouri 1 , * , Kambiz Forghanparast 2 , Abtin Heydarzadeh 3 , Mehrsima Abdollahzadeh 1 and Fatemeh Jahanyar Moghadam 1
Authors Information
1 Deaprtment of Anesthesiology, Guilan University of Medical Sciences, Rasht, Iran
2 Department of Microbiology, Guilan University of Medical Sciences, Rasht, Iran
3 Department of Community Medicine, Guilan University of Medical Sciences, Rasht, Iran
Article information
  • Anesthesiology and Pain Medicine: February 01, 2014, 4 (1); e14081
  • Published Online: February 7, 2014
  • Article Type: Research Article
  • Received: August 7, 2013
  • Revised: September 11, 2013
  • Accepted: September 21, 2013
  • DOI: 10.5812/aapm.14081

To Cite: Farzi F, Mirmansouri A, Forghanparast K, Heydarzadeh A, Abdollahzadeh M, et al. Addition of Intrathecal Fentanyl or Meperidine to Lidocaine and Epinephrine for Spinal Anesthesia in Elective Cesarean Delivery, Anesth Pain Med. 2014 ; 4(1):e14081. doi: 10.5812/aapm.14081.

Copyright © 2014, Iranian Society of Regional Anesthesia and Pain Medicine (ISRAPM). This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License ( which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Background
2. Objectives
3. Patients and Methods
4. Results
5. Discussion
  • 1. BirBach DJ, Browne IM. Miller's Anesthesia. 2010; : 2203-40
  • 2. Barash P, Cullen BF, Stoelting RK. Clinical anesthesia. 2001;
  • 3. Pournajafian A, Rokhtabnak F, Kholdbarin A, Ghodrati M, Ghavam S. Comparison of remifentanil and fentanyl regarding hemodynamic changes due to endotracheal intubation in preeclamptic parturient candidate for cesarean delivery. Anesth Pain Med. 2012; 2(2): 90-3[DOI][PubMed]
  • 4. Brown DL. Miller's Anesthesia. 2010; : 1611 – 38
  • 5. Block A, Covino BG. Effect of local anesthetic agents on cardiac conduction and contractility. Reg Anesth. 1981; 6: 55-61
  • 6. Shrestha BR, Maharjan SK, Thapa C. Comparative study between bupivacaine heavy vs pethidine intrathecally to study early haemodynamic changes and postoperative analgesia in patients undergoing caesarean section. Kathmandu Univ Med J (KUMJ). 2007; 5(2): 166-72[PubMed]
  • 7. Golfam P, Yari M, Bakhtiyari HR. Minimum appropriate dose of lidocaine with a fixed dose of sufentanil epinephrine used for spinal anesthesia in caesarian section. Anesth Pain Med. 2013; 2(3): 123-6[DOI][PubMed]
  • 8. Chung CJ, Yun SH, Hwang GB, Park JS, Chin YJ. Intrathecal fentanyl added to hyperbaric ropivacaine for cesarean delivery. Reg Anesth Pain Med. 2002; 27(6): 600-3[PubMed]
  • 9. Liu LL, Gropper MA. Postoperative analgesia and sedation in the adult intensive care unit: a guide to drug selection. Drugs. 2003; 63(8): 755-67[PubMed]
  • 10. Weigl W, Bierylo A, Krzemien-Wiczynska S, Mayzner-Zawadzka E. [Comparative study of postoperative analgesia after intrathecal administration of bupivacaine with fentanyl or morphine for elective Caesarean section]. Anestezjol Intens Ter. 2009; 41(1): 28-32[PubMed]
  • 11. Harsoor SS, Vikram MS. Spinal anesthesia with low dose bupivacaine with fentanyl for cesarean section. SAARC J Anesth. 2008; 1(2): 142-5
  • 12. Etezadi F, Karimi Yarandi K, Ahangary A, Shokri H, Imani F, Safari S, et al. The effect of needle type, duration of surgery and position of the patient on the risk of transient neurologic symptoms. Anesth Pain Med. 2013; 2(4): 154-8[DOI][PubMed]
  • 13. Shahriari A, Khooshideh M. Intrathecal fentanyl added to lidocaine for Cesarean delivery under spinal anesthesia--a randomised clinical trial. Middle East J Anesthesiol. 2007; 19(2): 397-406[PubMed]
  • 14. Connelly NR, Dunn SM, Ingold V, Villa EA. The use of fentanyl added to morphine-lidocaine-epinephrine spinal solution in patients undergoing cesarean section. Anesth Analg. 1994; 78(5): 918-20[PubMed]
  • 15. Anaraki AN, Mirzaei K. The Effect of Different Intrathecal Doses of Meperidine on Shivering during Delivery Under Spinal Anesthesia. Int J Prev Med. 2012; 3(10): 706-12[PubMed]
  • 16. Han JW, Kang HS, Choi SK, Park SJ, Park HJ, Lim TH. Comparison of the Effects of Intrathecal Fentanyl and Meperidine on Shivering after Cesarean Delivery under Spinal Anesthesia. Korean J Anesthesiol. 2007; 52(6): 657-62
  • 17. Yu SC, Ngan Kee WD, Kwan AS. Addition of meperidine to bupivacaine for spinal anaesthesia for Caesarean section. Br J Anaesth. 2002; 88(3): 379-83[PubMed]
  • 18. Chaudhari LS, Kane DG, Shivkumar B, Kamath SK. Comparative study of intrathecal pethidine versus lignocaine as an anaesthetic and a postoperative analgesic for perianal surgery. J Postgrad Med. 1996; 42(2): 43-5[PubMed]
  • 19. Bakhshaei MH, Manuchehrian N, Khoshraftar E, Mohamadipour-Anvary H, Sanatkarfar M. Analgesic effects of intrathecal sufentanil added to lidocaine 5% in elective cesarean section. Acta Med Iran. 2010; 48(6): 380-4[PubMed]
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