Anesthesiology and Pain Medicine

Published by: Kowsar

Evaluating the Incidence of Cognitive Disorder Following Off-Pump Coronary Artery Bypasses Surgery and its Predisposing Factors

Marjan Joudi 1 , Mehdi Fathi 2 , * , Hadi Harati 3 , Mitra Joudi 4 , Azra Izanloo 5 , Ali Rahdari 2 and Ghasem Soltani 2
Authors Information
1 Department of Surgery, Imam Reza Hospital, Mashhad University of Medical Sciences, Mashhad, Iran
2 Deapartment of Anesthesia, Imam Reza Hospital, Mashhad University of Medical Sciences, Mashhad, Iran
3 Department of Neurology, Imam Reza Hospital, Mashhad University of Medical Sciences, Mashhad, Iran
4 Department of Psychiatry, Faculty of Medicine, Golestan University of Medical Sciences, Gorgan, Iran
5 Department of Radiologic Technology, Faculty of Paramedical Sciences, Mashhad University of Medical Sciences, Mashhad, Iran
Article information
  • Anesthesiology and Pain Medicine: October 01, 2014, 4 (4); e18545
  • Published Online: September 15, 2014
  • Article Type: Research Article
  • Received: February 24, 2014
  • Revised: March 30, 2014
  • Accepted: April 30, 2014
  • DOI: 10.5812/aapm.18545

To Cite: Joudi M, Fathi M, Harati H, Joudi M, Izanloo A, et al. Evaluating the Incidence of Cognitive Disorder Following Off-Pump Coronary Artery Bypasses Surgery and its Predisposing Factors, Anesth Pain Med. 2014 ; 4(4):e18545. doi: 10.5812/aapm.18545.

Copyright © 2014, Iranian Society of Regional Anesthesia and Pain Medicine (ISRAPM). This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License ( which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Background
2. Objectives
3. Patients and Methods
4. Results
5. Discussion
  • 1. Trzepacz PT, Sclabassi RJ, Van Thiel DH. Delirium: a subcortical phenomenon? J Neuropsychiatry Clin Neurosci. 1989; 1(3): 283-90[PubMed]
  • 2. George C, Nair JS, Ebenezer JA, Gangadharan A, Christudas A, Gnanaseelan LK, et al. Validation of the Intensive Care Delirium Screening Checklist in nonintubated intensive care unit patients in a resource-poor medical intensive care setting in South India. J Crit Care. 2011; 26(2): 138-43[DOI][PubMed]
  • 3. Gandhi GY, Nuttall GA, Abel MD, Mullany CJ, Schaff HV, Williams BA, et al. Intraoperative hyperglycemia and perioperative outcomes in cardiac surgery patients. Mayo Clin Proc. 2005; 80(7): 862-6[DOI][PubMed]
  • 4. Rezaee F. Translation of Kaplan and Sudock Synopsis of Psyhiatry Behavioral Science. 2007; : 405-18
  • 5. Hall JB, Schweickert W, Kress JP. Role of analgesics, sedatives, neuromuscular blockers, and delirium. Crit Care Med. 2009; 37(10 Suppl)-21[DOI][PubMed]
  • 6. Deiner S, Silverstein JH. Postoperative delirium and cognitive dysfunction. Br J Anaesth. 2009; 103 Suppl 1-6[DOI][PubMed]
  • 7. Akechi T, Ishiguro C, Okuyama T, Endo C, Sagawa R, Uchida M, et al. Delirium training program for nurses. Psychosomatics. 2010; 51(2): 106-11[DOI][PubMed]
  • 8. Flagg B, Cox L, McDowell S, Mwose JM, Buelow JM. Nursing identification of delirium. Clin Nurse Spec. 2010; 24(5): 260-6[DOI][PubMed]
  • 9. Pandharipande P, Jackson J, Ely EW. Delirium: acute cognitive dysfunction in the critically ill. Curr Opin Crit Care. 2005; 11(4): 360-8[PubMed]
  • 10. Khan BA, Zawahiri M, Campbell NL, Fox GC, Weinstein EJ, Nazir A, et al. Delirium in hospitalized patients: implications of current evidence on clinical practice and future avenues for research--a systematic evidence review. J Hosp Med. 2012; 7(7): 580-9[DOI][PubMed]
  • 11. Stransky M, Schmidt C, Ganslmeier P, Grossmann E, Haneya A, Moritz S, et al. Hypoactive delirium after cardiac surgery as an independent risk factor for prolonged mechanical ventilation. J Cardiothorac Vasc Anesth. 2011; 25(6): 968-74[DOI][PubMed]
  • 12. Witlox J, Eurelings LS, de Jonghe JF, Kalisvaart KJ, Eikelenboom P, van Gool WA. Delirium in elderly patients and the risk of postdischarge mortality, institutionalization, and dementia: a meta-analysis. JAMA. 2010; 304(4): 443-51[DOI][PubMed]
  • 13. Schmitt EM, Marcantonio ER, Alsop DC, Jones RN, Rogers SO, Jr, Fong TG, et al. Novel risk markers and long-term outcomes of delirium: the successful aging after elective surgery (SAGES) study design and methods. J Am Med Dir Assoc. 2012; 13(9): 818 e1-10[DOI][PubMed]
  • 14. Maldonado JR, Wysong A, van der Starre PJ, Block T, Miller C, Reitz BA. Dexmedetomidine and the reduction of postoperative delirium after cardiac surgery. Psychosomatics. 2009; 50(3): 206-17[DOI][PubMed]
  • 15. Koster S, Hensens AG, Schuurmans MJ, van der Palen J. Risk factors of delirium after cardiac surgery: a systematic review. Eur J Cardiovasc Nurs. 2011; 10(4): 197-204[DOI][PubMed]
  • 16. Rolfson DB, McElhaney JE, Rockwood K, Finnegan BA, Entwistle LM, Wong JF, et al. Incidence and risk factors for delirium and other adverse outcomes in older adults after coronary artery bypass graft surgery. Can J Cardiol. 1999; 15(7): 771-6[PubMed]
  • 17. Chaput AJ, Bryson GL. Postoperative delirium: risk factors and management: continuing professional development. Can J Anaesth. 2012; 59(3): 304-20[DOI][PubMed]
  • 18. Mu DL, Wang DX, Li LH, Shan GJ, Su Y, Yu QJ, et al. [Postoperative delirium is associated with cognitive dysfunction one week after coronary artery bypass grafting surgery]. Beijing Da Xue Xue Bao. 2011; 43(2): 242-9[PubMed]
  • 19. Ganavati A, Forooghi M, Esmaeili S, Hasantash SA, Blourain AA, Shahzamani M, et al. The Relation between Post Cardiac Surgery Delirium and Intraoperative Factors. Iran J Surg. 2009; 17(3)
  • 20. Kaplan HI, Sadock BJ. Kaplan and Sadock's Synopsis of Psychiatry. 2003;
  • 21. Clayer M, Bruckner J. Occult hypoxia after femoral neck fracture. Psychiatry Neural. 1990; 3(4): 184-91
  • 22. Rockwood K, Cosway S, Carver D, Jarrett P, Stadnyk K, Fisk J. The risk of dementia and death after delirium. Age Ageing. 1999; 28(6): 551-6[PubMed]
  • 23. Miyazaki S, Yoshitani K, Miura N, Irie T, Inatomi Y, Ohnishi Y, et al. Risk factors of stroke and delirium after off-pump coronary artery bypass surgery. Interact Cardiovasc Thorac Surg. 2011; 12(3): 379-83[DOI][PubMed]
  • 24. Sapryigina LV, Belova LA, Burtsev SV, Belova NV, Elistratova DS, Koroleva AG. The etiology of moderate cognitive disorders (MCD) in a working-age population according to epidemiological studies. J Neurol Sci. 2013; 333[DOI]
Creative Commons License Except where otherwise noted, this work is licensed under Creative Commons Attribution Non Commercial 4.0 International License .

Search Relations:



Create Citiation Alert
via Google Reader

Readers' Comments