Anesthesiology and Pain Medicine

Published by: Kowsar

Intravenous Patient-Controlled Remifentanil Versus Paracetamol in Post-Operative Pain Management in Patients Undergoing Coronary Artery Bypass Graft Surgery

Alireza Jahangiri Fard 1 , Touraj Babaee 2 , Seyed Mostafa Alavi 2 , Ali Akbar Nasiri 3 , Seyed Mohamad Mehran Ghoreishi 2 , Noor Mohammad Noori 2 and Maziar Mahjoubifard 4 , *
Authors Information
1 Masih Daneshvari Institute of Tuberculosis and Lung Disease, Shahid Beheshti University of Medical Sciences, Tehran, Iran
2 Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, Iran
3 Department of Anesthesiology, Zabol University of Medical Sciences, Zabol, Iran
4 Research Center of Children and Adolescent Health, Ali-Ebn E-Abitaleb Hospital, Zahedan University of Medical Sciences, Zahedan, Iran
Article information
  • Anesthesiology and Pain Medicine: December 01, 2014, 4 (5); e19862
  • Published Online: September 16, 2014
  • Article Type: Research Article
  • Revised: June 5, 2014
  • Accepted: June 11, 2014
  • DOI: 10.5812/aapm.19862

To Cite: Jahangiri Fard A, Babaee T, Alavi S M, Nasiri A A, Ghoreishi S M M, et al. Intravenous Patient-Controlled Remifentanil Versus Paracetamol in Post-Operative Pain Management in Patients Undergoing Coronary Artery Bypass Graft Surgery, Anesth Pain Med. 2014 ; 4(5):e19862. doi: 10.5812/aapm.19862.

Copyright © 2014, Iranian Society of Regional Anesthesia and Pain Medicine (ISRAPM). This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License ( which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Background
2. Objectives
3. Materials and Methods
4. Results
5. Discussion
  • 1. Kim K, Kim WJ, Choi DK, Lee YK, Choi IC, Sim JY. The analgesic efficacy and safety of nefopam in patient-controlled analgesia after cardiac surgery: A randomized, double-blind, prospective study. J Int Med Res. 2014; 42(3): 684-92[DOI][PubMed]
  • 2. Sattari M, Baghdadchi ME, Kheyri M, Khakzadi H, Ozar Mashayekhi S. Study of patient pain management after heart surgery. Adv Pharm Bull. 2013; 3(2): 373-7[DOI][PubMed]
  • 3. Baltali S, Turkoz A, Bozdogan N, Demirturk OS, Baltali M, Turkoz R, et al. The efficacy of intravenous patient-controlled remifentanil versus morphine anesthesia after coronary artery surgery. J Cardiothorac Vasc Anesth. 2009; 23(2): 170-4[DOI][PubMed]
  • 4. Gurbet A, Goren S, Sahin S, Uckunkaya N, Korfali G. Comparison of analgesic effects of morphine, fentanyl, and remifentanil with intravenous patient-controlled analgesia after cardiac surgery. J Cardiothorac Vasc Anesth. 2004; 18(6): 755-8[DOI][PubMed]
  • 5. Krishnan K, Elliot SC, Berridge JC, Mallick A. Remifentanil patient-controlled analgesia following cardiac surgery. Acta Anaesthesiol Scand. 2005; 49(6): 876-9[DOI][PubMed]
  • 6. Yarmush J, D'Angelo R, Kirkhart B, O'Leary C, Pitts MC, 2nd, Graf G, et al. A comparison of remifentanil and morphine sulfate for acute postoperative analgesia after total intravenous anesthesia with remifentanil and propofol. Anesthesiology. 1997; 87(2): 235-43[PubMed]
  • 7. Bowdle TA, Camporesi EM, Maysick L, Hogue CW, Jr, Miguel RV, Pitts M, et al. A multicenter evaluation of remifentanil for early postoperative analgesia. Anesth Analg. 1996; 83(6): 1292-7[PubMed]
  • 8. Rauf K, Vohra A, Fernandez-Jimenez P, O'Keeffe N, Forrest M. Remifentanil infusion in association with fentanyl-propofol anaesthesia in patients undergoing cardiac surgery: effects on morphine requirement and postoperative analgesia. Br J Anaesth. 2005; 95(5): 611-5[DOI][PubMed]
  • 9. Hinz B, Cheremina O, Brune K. Acetaminophen (paracetamol) is a selective cyclooxygenase-2 inhibitor in man. FASEB J. 2008; 22(2): 383-90[DOI][PubMed]
  • 10. Eremenko AA, Kuslieva EV. [Analgesic and opioid-sparing effects of intravenous paracetamol in the early period after aortocoronary bypass surgery]. Anesteziol Reanimatol. 2008; (5): 11-4[PubMed]
  • 11. Pettersson PH, Jakobsson J, Owall A. Intravenous acetaminophen reduced the use of opioids compared with oral administration after coronary artery bypass grafting. J Cardiothorac Vasc Anesth. 2005; 19(3): 306-9[PubMed]
  • 12. Checketts MR, Gilhooly CJ, Kenny GN. Patient-maintained analgesia with target-controlled alfentanil infusion after cardiac surgery: a comparison with morphine PCA. Br J Anaesth. 1998; 80(6): 748-51[PubMed]
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