Anesthesiology and Pain Medicine

Published by: Kowsar

Neuroprotective Effect of Erythropoietin in Postoperation Cervical Spinal Cord Injury: Case Report and Review

Alireza Nekoui 1 , Violeta Del Carmen Escalante Tresierra 2 , Sadegh Abdolmohammadi 1 , Daniel Shedid 3 and Gilbert Blaise 1 , *
Authors Information
1 Anesthesiology and Pain Management Department, Centre hospitalier de l’Universite de Montreal (CHUM), Montreal, Canada
2 Anesthesiology Department, San Felipe Clinic, Lima, Peru
3 Neurosurgery Department, Centre hospitalier de l’Universite de Montreal (CHUM), Montreal, Canada
Article information
  • Anesthesiology and Pain Medicine: December 01, 2015, 5 (6); e28849
  • Published Online: November 28, 2015
  • Article Type: Case Report
  • Received: April 3, 2015
  • Revised: July 7, 2015
  • Accepted: September 10, 2015
  • DOI: 10.5812/aapm.28849

To Cite: Nekoui A, Del Carmen Escalante Tresierra V, Abdolmohammadi S, Shedid D, Blaise G. Neuroprotective Effect of Erythropoietin in Postoperation Cervical Spinal Cord Injury: Case Report and Review, Anesth Pain Med. 2015 ; 5(6):e28849. doi: 10.5812/aapm.28849.

Abstract
Copyright © 2015, Iranian Society of Regional Anesthesia and Pain Medicine (ISRAPM). This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Introduction
2. Case Presentation
3. Discussion
Acknowledgements
Footnote
References
  • 1. Ju G, Wang J, Wang Y, Zhao X. Spinal cord contusion. Neural Regen Res. 2014; 9(8): 789-94[DOI][PubMed]
  • 2. Mortazavi MM, Verma K, Harmon OA, Griessenauer CJ, Adeeb N, Theodore N, et al. The microanatomy of spinal cord injury: a review. Clin Anat. 2015; 28(1): 27-36[DOI][PubMed]
  • 3. Grasso G, Sfacteria A, Erbayraktar S, Passalacqua M, Meli F, Gokmen N, et al. Amelioration of spinal cord compressive injury by pharmacological preconditioning with erythropoietin and a nonerythropoietic erythropoietin derivative. J Neurosurg Spine. 2006; 4(4): 310-8[DOI][PubMed]
  • 4. Lund A, Lundby C, Olsen NV. High-dose erythropoietin for tissue protection. Eur J Clin Invest. 2014; 44(12): 1230-8[DOI][PubMed]
  • 5. Messe SR, McGarvey ML, Bavaria JE, Pochettino A, Szeto WY, Cheung AT, et al. A pilot study of darbepoetin alfa for prophylactic neuroprotection in aortic surgery. Neurocrit Care. 2013; 18(1): 75-80[DOI][PubMed]
  • 6. Loblaw DA, Holden L, Xenocostas A, Chen E, Chander S, Cooper P, et al. Functional and pharmacokinetic outcomes after a single intravenous infusion of recombinant human erythropoietin in patients with malignant extradural spinal cord compression. Clin Oncol (R Coll Radiol). 2007; 19(1): 63-70[PubMed]
  • 7. Hall ED, Springer JE. Neuroprotection and acute spinal cord injury: a reappraisal. NeuroRx. 2004; 1(1): 80-100[DOI][PubMed]
  • 8. Kwon BK, Okon E, Hillyer J, Mann C, Baptiste D, Weaver LC, et al. A systematic review of non-invasive pharmacologic neuroprotective treatments for acute spinal cord injury. J Neurotrauma. 2011; 28(8): 1545-88[DOI][PubMed]
  • 9. Lei B, Popp S, Capuano-Waters C, Cottrell JE, Kass IS. Lidocaine attenuates apoptosis in the ischemic penumbra and reduces infarct size after transient focal cerebral ischemia in rats. Neuroscience. 2004; 125(3): 691-701[DOI][PubMed]
  • 10. Bavarsad Shahripour R, Harrigan MR, Alexandrov AV. N-acetylcysteine (NAC) in neurological disorders: mechanisms of action and therapeutic opportunities. Brain Behav. 2014; 4(2): 108-22[DOI][PubMed]
  • 11. Robertson CS, Cherian L, Shah M, Garcia R, Navarro JC, Grill RJ, et al. Neuroprotection with an erythropoietin mimetic peptide (pHBSP) in a model of mild traumatic brain injury complicated by hemorrhagic shock. J Neurotrauma. 2012; 29(6): 1156-66[DOI][PubMed]
  • 12. Mennini T, De Paola M, Bigini P, Mastrotto C, Fumagalli E, Barbera S, et al. Nonhematopoietic erythropoietin derivatives prevent motoneuron degeneration in vitro and in vivo. Mol Med. 2006; 12(7-8): 153-60[DOI][PubMed]
  • 13. Ratilal BO, Arroja MM, Rocha JP, Fernandes AM, Barateiro AP, Brites DM, et al. Neuroprotective effects of erythropoietin pretreatment in a rodent model of transient middle cerebral artery occlusion. J Neurosurg. 2014; 121(1): 55-62[DOI][PubMed]
  • 14. Hassani V, Homaei MM, Shahbazi A, Zamani MM, Safari S, Nadi S, et al. Human erythropoietin effect in postoperative visual loss following spine surgery: a case report. Anesth Pain Med. 2014; 4(2)[DOI][PubMed]
  • 15. McPherson RJ, Juul SE. Erythropoietin for infants with hypoxic-ischemic encephalopathy. Curr Opin Pediatr. 2010; 22(2): 139-45[DOI][PubMed]
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