Anesthesiology and Pain Medicine

Published by: Kowsar

Effect of Intravenous Acetaminophen (Paracetamol) on Hemodynamic Parameters Following Endotracheal Tube Intubation and Postoperative Pain in Caesarian Section Surgeries

Ghasem Soltani 1 , Amirmasoud Molkizadeh 2 and Shahram Amini 1 , *
Authors Information
1 Department of Anesthesiology, Cardiac Anesthesia Research Center, Emam Reza Hospital, Mashhad University of Medical Sciences, Mashhad, Iran
2 Department of Anesthesiology, Emam Reza Hospital, Mashhad University of Medical Sciences, Mashhad, Iran
Article information
  • Anesthesiology and Pain Medicine: December 01, 2015, 5 (6); e30062
  • Published Online: December 5, 2015
  • Article Type: Research Article
  • Received: May 26, 2015
  • Revised: August 16, 2015
  • Accepted: August 31, 2015
  • DOI: 10.5812/aapm.30062

To Cite: Soltani G, Molkizadeh A, Amini S. Effect of Intravenous Acetaminophen (Paracetamol) on Hemodynamic Parameters Following Endotracheal Tube Intubation and Postoperative Pain in Caesarian Section Surgeries, Anesth Pain Med. 2015 ; 5(6):e30062. doi: 10.5812/aapm.30062.

Copyright © 2015, Iranian Society of Regional Anesthesia and Pain Medicine (ISRAPM). This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License ( which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Background
2. Objectives
3. Patients and Methods
4. Results
5. Discussion
  • 1. Beyer K, Taffe P, Halfon P, Pittet V, Pichard S, Haller G, et al. Hypertension and intra-operative incidents: a multicentre study of 125,000 surgical procedures in Swiss hospitals. Anaesthesia. 2009; 64(5): 494-502[DOI][PubMed]
  • 2. Goldman L, Caldera DL. Risks of general anesthesia and elective operation in the hypertensive patient. Anesthesiology. 1979; 50(4): 285-92[PubMed]
  • 3. Helfman SM, Gold MI, DeLisser EA, Herrington CA. Which drug prevents tachycardia and hypertension associated with tracheal intubation: lidocaine, fentanyl, or esmolol? Anesth Analg. 1991; 72(4): 482-6[PubMed]
  • 4. Omote K, Kirita A, Namiki A, Iwasaki H. Effects of nicardipine on the circulatory responses to tracheal intubation in normotensive and hypertensive patients. Anaesthesia. 1992; 47(1): 24-7[PubMed]
  • 5. Sener M, Kocum A, Caliskan E, Yilmaz I, Caylakli F, Aribogan A. [Administration of paracetamol versus dipyrone by intravenous patient-controlled analgesia for postoperative pain relief in children after tonsillectomy.]. Rev Bras Anestesiol. 2014; [DOI][PubMed]
  • 6. Kaur Makkar J, Jain K, Bhatia N, Jain V, Mal Mithrawal S. Comparison of analgesic efficacy of paracetamol and tramadol for pain relief in active labor. J Clin Anesth. 2015; 27(2): 159-63[DOI][PubMed]
  • 7. Majumdar S, Das A, Kundu R, Mukherjee D, Hazra B, Mitra T. Intravenous paracetamol infusion: Superior pain management and earlier discharge from hospital in patients undergoing palliative head-neck cancer surgery. Perspect Clin Res. 2014; 5(4): 172-7[DOI][PubMed]
  • 8. Shimia M, Parish M, Abedini N. The effect of intravenous paracetamol on postoperative pain after lumbar discectomy. Asian Spine J. 2014; 8(4): 400-4[DOI][PubMed]
  • 9. Oreskovic Z, Bicanic G, Hrabac P, Tripkovic B, Delimar D. Treatment of postoperative pain after total hip arthroplasty: comparison between metamizol and paracetamol as adjunctive to opioid analgesics-prospective, double-blind, randomised study. Arch Orthop Trauma Surg. 2014; 134(5): 631-6[DOI][PubMed]
  • 10. Mohamad AH, McDonnell NJ, Bloor M, Nathan EA, Paech MJ. Parecoxib and paracetamol for pain relief following minor day-stay gynaecological surgery. Anaesth Intensive Care. 2014; 42(1): 43-50[PubMed]
  • 11. Iorno V, Landi L, Di Pasquale R, Cicenia S, Moschini V. Comparison of intravenous ketorolac with or without paracetamol in postoperative pain control following ambulatory surgery. Curr Med Res Opin. 2013; 29(12): 1685-90[DOI][PubMed]
  • 12. Tunali Y, Akcil EF, Dilmen OK, Tutuncu AC, Koksal GM, Akbas S, et al. Efficacy of intravenous paracetamol and dexketoprofen on postoperative pain and morphine consumption after a lumbar disk surgery. J Neurosurg Anesthesiol. 2013; 25(2): 143-7[DOI][PubMed]
  • 13. Evron S, Ezri T, Protianov M, Muzikant G, Sadan O, Herman A, et al. The effects of remifentanil or acetaminophen with epidural ropivacaine on body temperature during labor. J Anesth. 2008; 22(2): 105-11[DOI][PubMed]
  • 14. Darvish H, Memar Ardestani B, Mohammadkhani Shali S, Tajik A. Analgesic Efficacy of Diclofenac and Paracetamol vs. Meperidine in Cesarean Section. Anesth Pain Med. 2014; 4(1)[DOI][PubMed]
  • 15. Inal MT, Cel N, Tuncay F. I.V. Paracetamol Infusion is beter than IV meperidine infusion for postoperative analgesia after caesarean section. Internet J Anesthesiol. 2007; 13(1): 112-9
  • 16. Akhavanakbari G, Entezariasl M, Isazadehfar K, Kahnamoyiagdam F. The effects of indomethacin, diclofenac, and acetaminophen suppository on pain and opioids consumption after cesarean section. Perspect Clin Res. 2013; 4(2): 136-41[DOI][PubMed]
  • 17. Omar AAA, Issa KAA. Intravenous Paracetamol (Perfalgan) for analgesia after cesarean section: A double-blind randomized controlled study. RMJ. 2011; 36(4): 269-73
  • 18. Ayatollahi V, Faghihi S, Behdad S, Heiranizadeh N, Baghianimoghadam B. Effect of preoperative administration of intravenous paracetamol during cesarean surgery on hemodynamic variables relative to intubation, postoperative pain and neonatal apgar. Acta Clin Croat. 2014; 53(3): 272-8[PubMed]
  • 19. Atashkhoyi S, Rasouli S, Fardiazar Z, Ghojazadeh M, Hatami Marandi P. Preventive Analgesia with Intravenous Paracetamol for Post-cesarean section Pain Control. Int J Womens Health. 2014; 2(3): 131-7[DOI]
  • 20. Schug SA, Manopas A. Update on the role of non-opioids for postoperative pain treatment. Best Pract Res Clin Anaesthesiol. 2007; 21(1): 15-30[PubMed]
  • 21. Tabari M, Alipour M, Asadpour A, Mogharabian N, Amini S. A Comparison Between Intravenous Acetaminophen (Paracetamol) and Intravenous Meperidine in Postoperative Pain Reduction of Patients Undergoing Appendectomy. Razavi Int J Med. 2014; 2(1)[DOI]
  • 22. Atef A, Fawaz AA. Intravenous paracetamol is highly effective in pain treatment after tonsillectomy in adults. Eur Arch Otorhinolaryngol. 2008; 265(3): 351-5[DOI][PubMed]
  • 23. Alhashemi JA, Daghistani MF. Effects of intraoperative i.v. acetaminophen vs i.m. meperidine on post-tonsillectomy pain in children. Br J Anaesth. 2006; 96(6): 790-5[DOI][PubMed]
  • 24. Amini S, Shakib M. Hemodynamic Changes Following Endotracheal Intubation in Patients Undergoing Cesarean Section With General Anesthesia: Application of Glidescope® Videolaryngoscope Versus Direct Laryngoscope. Anesth Pain Med. 2015; 5(2)[DOI]
  • 25. Hassan HI. Perioperative analgesic effects of intravenous paracetamol: Preemptive versus preventive analgesia in elective cesarean section. Anesth Essays Res. 2014; 8(3): 339-44[DOI][PubMed]
Creative Commons License Except where otherwise noted, this work is licensed under Creative Commons Attribution Non Commercial 4.0 International License .

Search Relations:



Create Citiation Alert
via Google Reader

Readers' Comments