Anesthesiology and Pain Medicine

Published by: Kowsar

Role of Hematocrit Concentration on Successful Extubation in Critically Ill Patients in the Intensive Care Units

Mohammad Taghi Beigmohammadi 1 , Zahid Hussain Khan 1 , * , Shahram Samadi 1 , Ata Mahmoodpoor 2 , Akbar Fotouhi 3 , Abbas Rahimiforoushani 3 and Mehrnaz Asadi Gharabaghi 4
Authors Information
1 Department of Anesthesiology and Intensive Care, Imam Khomeini Hospital Complex, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran
2 Cardiovascular Research Center, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran
3 Department of Epidemiology and Statistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
4 Division of Respiratory Disease, Department of Internal Medicine, Imam Khomeini Hospital Complex, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran
Article information
  • Anesthesiology and Pain Medicine: February 01, 2016, 6 (1); e32904
  • Published Online: January 16, 2016
  • Article Type: Research Article
  • Received: September 2, 2015
  • Revised: September 21, 2015
  • Accepted: October 19, 2015
  • DOI: 10.5812/aapm.32904

To Cite: Beigmohammadi M T, Hussain Khan Z, Samadi S, Mahmoodpoor A, Fotouhi A, et al. Role of Hematocrit Concentration on Successful Extubation in Critically Ill Patients in the Intensive Care Units, Anesth Pain Med. 2016 ; 6(1):e32904. doi: 10.5812/aapm.32904.

Copyright © 2016, Iranian Society of Regional Anesthesia and Pain Medicine (ISRAPM). This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License ( which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Background
2. Objectives
3. Materials and Methods
4. Results
5. Discussion
  • 1. Seymour CW, Martinez A, Christie JD, Fuchs BD. The outcome of extubation failure in a community hospital intensive care unit: a cohort study. Crit Care. 2004; 8(5)-7[DOI][PubMed]
  • 2. Kulkarni AP, Agarwal V. Extubation failure in intensive care unit: predictors and management. Indian J Crit Care Med. 2008; 12(1): 1-9[DOI][PubMed]
  • 3. Yang KL, Tobin MJ. A prospective study of indexes predicting the outcome of trials of weaning from mechanical ventilation. N Engl J Med. 1991; 324(21): 1445-50[DOI][PubMed]
  • 4. Smina M, Salam A, Khamiees M, Gada P, Amoateng-Adjepong Y, Manthous CA. Cough peak flows and extubation outcomes. Chest. 2003; 124(1): 262-8[PubMed]
  • 5. Martinez A, Seymour C, Nam M. Minute ventilation recovery time: a predictor of extubation outcome. Chest. 2003; 123(4): 1214-21[PubMed]
  • 6. Epstein SK. Predicting extubation failure: is it in (on) the cards? Chest. 2001; 120(4): 1061-3[PubMed]
  • 7. Epstein SK, Ciubotaru RL. Independent effects of etiology of failure and time to reintubation on outcome for patients failing extubation. Am J Respir Crit Care Med. 1998; 158(2): 489-93[DOI][PubMed]
  • 8. Khamiees M, Raju P, DeGirolamo A, Amoateng-Adjepong Y, Manthous CA. Predictors of extubation outcome in patients who have successfully completed a spontaneous breathing trial. Chest. 2001; 120(4): 1262-70[PubMed]
  • 9. Corwin HL, Parsonnet KC, Gettinger A. RBC transfusion in the ICU. Is there a reason? Chest. 1995; 108(3): 767-71[PubMed]
  • 10. Hebert PC, Blajchman MA, Cook DJ, Yetisir E, Wells G, Marshall J, et al. Do blood transfusions improve outcomes related to mechanical ventilation? Chest. 2001; 119(6): 1850-7[PubMed]
  • 11. Nelson AH, Fleisher LA, Rosenbaum SH. Relationship between postoperative anemia and cardiac morbidity in high-risk vascular patients in the intensive care unit. Crit Care Med. 1993; 21(6): 860-6[PubMed]
  • 12. Elia S, Liu P, Hilgenberg A, Skourtis C, Lappas D. Coronary haemodynamics and myocardial metabolism during weaning from mechanical ventilation in cardiac surgical patients. Can J Anaesth. 1991; 38(5): 564-71[DOI][PubMed]
  • 13. Jubran A, Tobin MJ. Pathophysiologic basis of acute respiratory distress in patients who fail a trial of weaning from mechanical ventilation. Am J Respir Crit Care Med. 1997; 155(3): 906-15[DOI][PubMed]
  • 14. Mohsenifar Z, Hay A, Hay J, Lewis MI, Koerner SK. Gastric intramural pH as a predictor of success or failure in weaning patients from mechanical ventilation. Ann Intern Med. 1993; 119(8): 794-8[PubMed]
  • 15. Schonhofer B, Wenzel M, Geibel M, Kohler D. Blood transfusion and lung function in chronically anemic patients with severe chronic obstructive pulmonary disease. Crit Care Med. 1998; 26(11): 1824-8[PubMed]
  • 16. Schonhofer B, Bohrer H, Kohler D. Blood transfusion facilitating difficult weaning from the ventilator. Anaesthesia. 1998; 53(2): 181-4[PubMed]
  • 17. Jubran A, Mathru M, Dries D, Tobin MJ. Continuous recordings of mixed venous oxygen saturation during weaning from mechanical ventilation and the ramifications thereof. Am J Respir Crit Care Med. 1998; 158(6): 1763-9[DOI][PubMed]
  • 18. Lemaire F, Teboul JL, Cinotti L, Giotto G, Abrouk F, Steg G, et al. Acute left ventricular dysfunction during unsuccessful weaning from mechanical ventilation. Anesthesiology. 1988; 69(2): 171-9[PubMed]
  • 19. Gandhi SK, Powers JC, Nomeir AM, Fowle K, Kitzman DW, Rankin KM, et al. The pathogenesis of acute pulmonary edema associated with hypertension. N Engl J Med. 2001; 344(1): 17-22[DOI][PubMed]
  • 20. Poppas A, Rounds S. Congestive heart failure. Am J Respir Crit Care Med. 2002; 165(1): 4-8[DOI][PubMed]
  • 21. De Jonghe B, Sharshar T, Lefaucheur JP, Authier FJ, Durand-Zaleski I, Boussarsar M, et al. Paresis acquired in the intensive care unit: a prospective multicenter study. JAMA. 2002; 288(22): 2859-67[PubMed]
  • 22. de Jonghe B, Lacherade JC, Sharshar T, Outin H. Intensive care unit-acquired weakness: risk factors and prevention. Crit Care Med. 2009; 37(10 Suppl)-15[DOI][PubMed]
  • 23. Coplin WM, Pierson DJ, Cooley KD, Newell DW, Rubenfeld GD. Implications of extubation delay in brain-injured patients meeting standard weaning criteria. Am J Respir Crit Care Med. 2000; 161(5): 1530-6[DOI][PubMed]
  • 24. Richard C. Tissue hypoxia. How to detect, how to correct, how to prevent? Intensive Care Med. 1996; 22(11): 1250-7[PubMed]
  • 25. Berg JM, Tymoczko JL, Stryer L. Hemoglobin Transports Oxygen Efficiently by Binding Oxygen Cooperatively. Biochemistry. 5th ed. New York: W H Freeman; 2002; : 414-21
  • 26. Edwards Lifesciences - LLC - Normal Hemodynamic Parameters - Adult 2009. 2009;
  • 27. McLellan SA, Walsh TS. Oxygen delivery and haemoglobin. Contin Educ Anaesth Critic Care Pain. 2004; 4(4): 123-6[DOI]
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