Anesthesiology and Pain Medicine

Published by: Kowsar

Comparison of the Effects of Low-Dose Midazolam, Magnesium Sulfate, Remifentanil and Low-Dose Etomidate on Prevention of Etomidate-Induced Myoclonus in Orthopedic Surgeries

Abbas Sedighinejad 1 , Bahram Naderi Nabi 1 , Mohammad Haghighi 1 , Gelareh Biazar 1 , * , Vali Imantalab 1 , Siamak Rimaz 1 and Zahra Zaridoost 1
Authors Information
1 Anesthesiology Research Center, Guilan University of Medical Sciences (GUMS), Rasht, Iran
Article information
  • Anesthesiology and Pain Medicine: April 01, 2016, 6 (2); e35333
  • Published Online: April 2, 2016
  • Article Type: Research Article
  • Received: December 7, 2015
  • Revised: December 25, 2015
  • Accepted: January 9, 2016
  • DOI: 10.5812/aapm.35333

To Cite: Sedighinejad A, Naderi Nabi B, Haghighi M, Biazar G, Imantalab V, et al. Comparison of the Effects of Low-Dose Midazolam, Magnesium Sulfate, Remifentanil and Low-Dose Etomidate on Prevention of Etomidate-Induced Myoclonus in Orthopedic Surgeries, Anesth Pain Med. 2016 ; 6(2):e35333. doi: 10.5812/aapm.35333.

Abstract
Copyright © 2016, Iranian Society of Regional Anesthesia and Pain Medicine (ISRAPM). This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Background
2. Objectives
3. Patients and Methods
4. Results
5. Discussion
Acknowledgements
Footnotes
References
  • 1. Luan HF, Zhao ZB, Feng JY, Cui JZ, Zhang XB, Zhu P, et al. Prevention of etomidate-induced myoclonus during anesthetic induction by pretreatment with dexmedetomidine. Braz J Med Biol Res. 2015; 48(2): 186-90[DOI][PubMed]
  • 2. Zhao X, Bao R, Zhu J, Liu Z, Meng Y, Fan X, et al. Pretreatment with butorphanol reduces myoclonus after etomidate. J Anesthesiol Clin Sci. 2013; 2(1): 2[DOI]
  • 3. Soleimanpour H, Safari S, Rahmani F, Jafari Rouhi A, Alavian SM. Intravenous hypnotic regimens in patients with liver disease; a review article. Anesth Pain Med. 2015; 5(1)[DOI][PubMed]
  • 4. Isitemiz I, Uzman S, Toptas M, Vahapoglu A, Gul YG, Inal FY, et al. Prevention of etomidate-induced myoclonus: which is superior: Fentanyl, midazolam, or a combination? A Retrospective comparative study. Med Sci Monit. 2014; 20: 262-7[DOI][PubMed]
  • 5. Safavi M, Honarmand A, Sahaf AS, Sahaf SM, Attari M, Payandeh M, et al. Magnesium sulfate versus Lidocaine pretreatment for prevention of pain on etomidate injection: A randomized, double-blinded placebo controlled trial. J Res Pharm Pract. 2015; 4(1): 4-8[DOI][PubMed]
  • 6. Ko BJ, Oh JN, Lee JH, Choi SR, Lee SC, Chung CJ. Comparison of effects of fentanyl and remifentanil on hemodynamic response to endotracheal intubation and myoclonus in elderly patients with etomidate induction. Korean J Anesthesiol. 2013; 64(1): 12-8[DOI][PubMed]
  • 7. Vuyk JSE, Reekers M. Miller's anesthesia. 2015;
  • 8. Factor S, Lang A, Weiner W. Drug induced movement disorders. 2008;
  • 9. He L, Ding Y, Chen H, Qian Y, Li Z. Butorphanol pre-treatment prevents myoclonus induced by etomidate: a randomised, double-blind, controlled clinical trial. Swiss Med Wkly. 2014; 144[DOI][PubMed]
  • 10. Bruder EA, Ball IM, Ridi S, Pickett W, Hohl C. Single induction dose of etomidate versus other induction agents for endotracheal intubation in critically ill patients. Cochrane Database Syst Rev. 2015; 1[DOI][PubMed]
  • 11. Doenicke AW, Roizen MF, Kugler J, Kroll H, Foss J, Ostwald P. Reducing myoclonus after etomidate. Anesthesiology. 1999; 90(1): 113-9[PubMed]
  • 12. Faught E. Clinical presentations and phenomenology of myoclonus. Epilepsia. 2003; 44 Suppl 11: 7-12[PubMed]
  • 13. Caviness JN. Myoclonus 1996;
  • 14. Yılmaz Cakirgoz M, Demirel I, Duran E, Ozer AB, Hancı V, Türkmen UA, et al. Effect of gabapentin pretreatment on myoclonus after etomidate: a randomized, double-blind, placebo-controlled study. Braz J Anesthesiol. 2015; [DOI]
  • 15. Do SH, Han SH, Park SH, Kim JH, Hwang JY, Son IS, et al. The effect of injection rate on etomidate-induced myoclonus. Korean J Anesthesiol. 2008; 55(3): 305[DOI]
  • 16. Lee SW, Gill HJ, Park SC, Kim JY, Kim JH, Lee JY, et al. The effect of remifentanil for reducing myoclonus during induction of anesthesia with etomidate. Korean J Anesthesiol. 2009; 57(4): 438[DOI]
  • 17. Nooraei N, Solhpour A, Mohajerani SA. Priming with atracurium efficiently suppresses etomidate-induced myoclonus. Acta Anaesthesiol Taiwan. 2013; 51(4): 145-8[DOI][PubMed]
  • 18. Hueter L, Schwarzkopf K, Simon M, Bredle D, Fritz H. Pretreatment with sufentanil reduces myoclonus after etomidate. Acta Anaesthesiol Scand. 2003; 47(4): 482-4[PubMed]
  • 19. Sutter R, Ristic A, Ruegg S, Fuhr P. Myoclonus in the critically ill: Diagnosis, management, and clinical impact. Clin Neurophysiol. 2016; 127(1): 67-80[DOI][PubMed]
  • 20. Salim B, Siddiqui SZ, Shamim F, Haider S. Effectiveness of Midazolam in the Prevention of Etomidate Induced Myoclonus. J Anesth Clin Res. 2015; 2015
  • 21. Un B, Ceyhan D, Yelken B. Prevention of etomidate-related myoclonus in anesthetic induction by pretreatment with magnesium. J Res Med Sci. 2011; 16(11): 1490-4[PubMed]
  • 22. Kelsaka E, Karakaya D, Sarihasan B, Baris S. Remifentanil pretreatment reduces myoclonus after etomidate. J Clin Anesth. 2006; 18(2): 83-6[DOI][PubMed]
  • 23. Ri HS, Shin SW, Kim TK, Baik SW, Yoon JU, Byeon GJ. The proper effect site concentration of remifentanil for prevention of myoclonus after etomidate injection. Korean J Anesthesiol. 2011; 61(2): 127-32[DOI][PubMed]
  • 24. Zou L, Yuan H, Wang HY, Geng ZY, Xu L, Sun L. [Role of target controlled infusion of remifentanil for the prevention of etomidate induced myoclonus during general anesthesia]. Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2013; 35(1): 112-5[PubMed]
  • 25. Schwarzkopf KR, Hueter L, Simon M, Fritz HG. Midazolam pretreatment reduces etomidate-induced myoclonic movements. Anaesth Intensive Care. 2003; 31(1): 18-20[PubMed]
  • 26. Wasinwong W, Uakritdathikar T, Kovitwanawong N, Pakam P. Prevention of Etomidate-Induced Myoclonic Movement After Midazolam Co-Induction with Low-Dose Etomidate. Songklanagarind Med J. 2011; 29(1): 1-9
  • 27. Huter L, Schreiber T, Gugel M, Schwarzkopf K. Low-dose intravenous midazolam reduces etomidate-induced myoclonus: a prospective, randomized study in patients undergoing elective cardioversion. Anesth Analg. 2007; 105(5): 1298-302[DOI][PubMed]
  • 28. Gultop F, Akkaya T, Bedirli N, Gumus H. Lidocaine pretreatment reduces the frequency and severity of myoclonus induced by etomidate. J Anesth. 2010; 24(2): 300-2[DOI][PubMed]
  • 29. Guler A, Satilmis T, Akinci SB, Celebioglu B, Kanbak M. Magnesium sulfate pretreatment reduces myoclonus after etomidate. Anesth Analg. 2005; 101(3): 705-9[DOI][PubMed]
  • 30. Choi JM, Choi IC, Jeong YB, Kim TH, Hahm KD. Pretreatment of rocuronium reduces the frequency and severity of etomidate-induced myoclonus. J Clin Anesth. 2008; 20(8): 601-4[DOI][PubMed]
  • 31. Mizrak A, Koruk S, Bilgi M, Kocamer B, Erkutlu I, Ganidagli S, et al. Pretreatment with dexmedetomidine or thiopental decreases myoclonus after etomidate: a randomized, double-blind controlled trial. J Surg Res. 2010; 159(1)-6[DOI][PubMed]
  • 32. Lv Z, Fang J, Zhu J, Liang B, Li F, Jiang S, et al. Intravenous dezocine pretreatment reduces the incidence and intensity of myoclonus induced by etomidate. J Anesth. 2014; 28(6): 944-7[DOI][PubMed]
  • 33. Carlos R, Innerarity S. Effect of premedication on etomidate anaesthesia. Br J Anaesth. 1979; 51(12): 1159-62[PubMed]
  • 34. El Bakry AEA, Marey H. The effect of gabapentin premedication on pain and anxiety during cataract surgery under peribulbar block. Egypt J Anaesth. 2012; 28(1): 43-7
  • 35. Caumo W, Schmidt AP, Schneider CN, Bergmann J, Iwamoto CW, Bandeira D, et al. Risk factors for preoperative anxiety in adults. Acta Anaesthesiol Scand. 2001; 45(3): 298-307[PubMed]
  • 36. Reddy RV, Moorthy SS, Dierdorf SF, Deitch RJ, Link L. Excitatory effects and electroencephalographic correlation of etomidate, thiopental, methohexital, and propofol. Anesth Analg. 1993; 77(5): 1008-11[PubMed]
  • 37. Hwang JY, Kim JH, Oh AY, Do SH, Jeon YT, Han SH. A comparison of midazolam with remifentanil for the prevention of myoclonic movements following etomidate injection. J Int Med Res. 2008; 36(1): 17-22[PubMed]
  • 38. Vuyk J, Reekers M. Miller's anesthesia. 2015; : 842-3
  • 39. Korttila K, Tammisto T, Aromaa U. Comparison of etomidate in combination with fentanyl or diazepam, with thiopentone as an induction agent for general anaesthesia. Br J Anaesth. 1979; 51(12): 1151-7[PubMed]
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