Anesthesiology and Pain Medicine

Published by: Kowsar

The Effect of Low-Level Laser on Postoperative Pain After Tibial Fracture Surgery: A Double-Blind Controlled Randomized Clinical Trial

Sholeh Nesioonpour 1 , Soheila Mokmeli 2 , Salman Vojdani 1 , * , Ahmadreza Mohtadi 1 , Reza Akhondzadeh 1 , Kaveh Behaeen 1 , Shahnam Moosavi 3 and Sarah Hojjati 4
Authors Information
1 Department of Anesthesiology, Pain Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
2 Canadian Optic and Laser Center, COL Center, Victoria, Canada
3 Department of Orthopedic, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
4 Department of Physical Education and Sport Science, Bu-Ali Sina University, Hamedan, Iran
Article information
  • Anesthesiology and Pain Medicine: August 01, 2014, 4 (3); e17350
  • Published Online: June 21, 2014
  • Article Type: Research Article
  • Received: January 14, 2014
  • Revised: February 15, 2014
  • Accepted: February 24, 2014
  • DOI: 10.5812/aapm.17350

To Cite: Nesioonpour S, Mokmeli S, Vojdani S, Mohtadi A, Akhondzadeh R, et al. The Effect of Low-Level Laser on Postoperative Pain After Tibial Fracture Surgery: A Double-Blind Controlled Randomized Clinical Trial, Anesth Pain Med. 2014 ; 4(3):e17350. doi: 10.5812/aapm.17350.

Copyright © 2014, Iranian Society of Regional Anesthesia and Pain Medicine (ISRAPM). This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License ( which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Background
2. Objectives
3. Patients and Methods
4. Results
5. Discussion
  • 1. Imani F, Rahimzadeh P, Faiz SH. Comparison the efficacy of adding clonidine, chloropromazine, promethazine and midazolam to morphine pumps in postoperative pain control of addicted patients. Anesth Pain Med. 2011; 1(1): 10-4[DOI]
  • 2. Shoar S, Esmaeili S, Safari S. Pain Management After Surgery: A Brief Review . Anesth Pain Med. 2012; 1(3): 184-6[DOI]
  • 3. Ledowski T, Reimer M, Chavez V, Kapoor V, Wenk M. Effects of acute postoperative pain on catecholamine plasma levels, hemodynamic parameters, and cardiac autonomic control. Pain. 2012; 153(4): 759-64[DOI][PubMed]
  • 4. Nesioonpour S, Akhondzadeh R, Pipelzadeh MR, Rezaee S, Nazaree E, Soleymani M. The effect of preemptive analgesia with bupivacaine on postoperative pain of inguinal hernia repair under spinal anesthesia: a randomized clinical trial. Hernia 2013; 17(4): 465-70[DOI][PubMed]
  • 5. Hosseini Jahromi SA, Sadeghi poor S, Hosseini Valami SM, Javadi A. Effects of Suppository Acetaminophen, Bupivacaine Wound Infiltration, and Caudal Block With Bupivacaine on Postoperative Pain in Pediatric Inguinal Herniorrhaphy. Anesth Pain Med. 2012; 1(4): 243-7[DOI]
  • 6. Apfelbaum JL, Chen C, Mehta SS, Gan TJ. Postoperative pain experience: results from a national survey suggest postoperative pain continues to be undermanaged. Anesth Analg. 2003; 97(2): 534-40[PubMed]
  • 7. Imani F, Rahimzadeh P. Gabapentinoids: gabapentin and pregabalin for postoperative pain management. Anesth Pain Med. 2012; 2(2): 52-3[DOI][PubMed]
  • 8. Nayman J. Measurement and control of postoperative pain. Ann R Coll Surg Engl. 1979; 61(6): 419-26[PubMed]
  • 9. Sieber FE, Mears S, Lee H, Gottschalk A. Postoperative opioid consumption and its relationship to cognitive function in older adults with hip fracture. J Am Geriatr Soc. 2011; 59(12): 2256-62[DOI][PubMed]
  • 10. Altunkaya H, Ozer Y, Kargi E, Ozkocak I, Hosnuter M, Demirel CB, et al. The postoperative analgesic effect of tramadol when used as subcutaneous local anesthetic. Anesth Analg. 2004; 99(5): 1461-4[DOI][PubMed]
  • 11. Asnaashari M, Safavi N. Application of Low level Lasers in Dentistry (Endodontic). J Lasers Med Sci. 2013; 4(2): 57-66
  • 12. Prabhu V, Rao SB, Chandra S, Kumar P, Rao L, Guddattu V, et al. Spectroscopic and histological evaluation of wound healing progression following Low Level Laser Therapy (LLLT). J Biophotonics. 2012; 5(2): 168-84[DOI][PubMed]
  • 13. Bjordal JM, Johnson MI, Iversen V, Aimbire F, Lopes-Martins RA. Low-level laser therapy in acute pain: a systematic review of possible mechanisms of action and clinical effects in randomized placebo-controlled trials. Photomed Laser Surg. 2006; 24(2): 158-68[DOI][PubMed]
  • 14. Hopkins JT, McLoda TA, Seegmiller JG, David Baxter G. Low-Level Laser Therapy Facilitates Superficial Wound Healing in Humans: A Triple-Blind, Sham-Controlled Study. J Athl Train. 2004; 39(3): 223-9[PubMed]
  • 15. Hegedus B, Viharos L, Gervain M, Galfi M. The effect of low-level laser in knee osteoarthritis: a double-blind, randomized, placebo-controlled trial. Photomed Laser Surg. 2009; 27(4): 577-84[DOI][PubMed]
  • 16. Carvalho RL, Alcantara PS, Kamamoto F, Cressoni MD, Casarotto RA. Effects of low-level laser therapy on pain and scar formation after inguinal herniation surgery: a randomized controlled single-blind study. Photomed Laser Surg. 2010; 28(3): 417-22[DOI][PubMed]
  • 17. Ribeiro AS, Salles PR, da Silva TA, Mesquita RA. A review of the nonsurgical treatment of oral leukoplakia. Int J Dent. 2010; 2010: 186018[DOI][PubMed]
  • 18. Chauhan A, Sarin P. Low level laser therapy in treatment of stress fractures tibia: A prospective randomized trial. Med J Armed Force Ind. 2006; 62(1): 27-9[DOI]
  • 19. Rubio Pascual P, de la Cruz Bertolo J. [Pediatric acute postoperative pain management service: 6 years' experience]. Rev Esp Anestesiol Reanim. 2006; 53(6): 346-53[PubMed]
  • 20. Gramke HF, de Rijke JM, van Kleef M, Raps F, Kessels AG, Peters ML, et al. The prevalence of postoperative pain in a cross-sectional group of patients after day-case surgery in a university hospital. Clin J Pain. 2007; 23(6): 543-8[DOI][PubMed]
  • 21. Moore KC, Hira N, Cruikshank JA. The Effect of Infra-Red Diode Laser Irradiation on the Duration and Severity of Postoperative Pain: A Double Blind Trial. Laser T. 1992; 4(4): 145-9[DOI]
  • 22. Brumback RJ, Ellison TS, Poka A, Bathon GH, Burgess AR. Intramedullary nailing of femoral shaft fractures. Part III: Long-term effects of static interlocking fixation. J Bone Joint Surg Am. 1992; 74(1): 106-12[PubMed]
  • 23. Jackson R, Roche G, Mangione T. Low-level laser therapy effectiveness for reducing pain after breast augmentation. Am J Cosmet Surg. 2009; 26(3): 144-8
  • 24. de Almeida P, Lopes-Martins RA, De Marchi T, Tomazoni SS, Albertini R, Correa JC, et al. Red (660 nm) and infrared (830 nm) low-level laser therapy in skeletal muscle fatigue in humans: what is better? Lasers Med Sci. 2012; 27(2): 453-8[DOI][PubMed]
  • 25. Doshi-Mehta G, Bhad-Patil WA. Efficacy of low-intensity laser therapy in reducing treatment time and orthodontic pain: A clinical investigation. Am J Orthod Dentofac . 2012; 141(3): 289-97[DOI]
  • 26. Obradovic R, Kesic L, Mihailovic D, Antic S, Jovanovic G, Petrovic A, et al. A histological evaluation of a low-level laser therapy as an adjunct to periodontal therapy in patients with diabetes mellitus. Lasers Med Sci. 2013; 28(1): 19-24[DOI][PubMed]
  • 27. Artes-Ribas M, Arnabat-Dominguez J, Puigdollers A. Analgesic effect of a low-level laser therapy (830 nm) in early orthodontic treatment. Lasers Med Sci. 2013; 28(1): 335-41[DOI][PubMed]
  • 28. Kreisler MB, Haj HA, Noroozi N, Willershausen B. Efficacy of low level laser therapy in reducing postoperative pain after endodontic surgery-- a randomized double blind clinical study. Int J Oral Maxillofac Surg. 2004; 33(1): 38-41[PubMed]
  • 29. Bjordal JM, Lopes-Martins RA, Joensen J, Couppe C, Ljunggren AE, Stergioulas A, et al. A systematic review with procedural assessments and meta-analysis of low level laser therapy in lateral elbow tendinopathy (tennis elbow). BMC Musculoskelet Disord. 2008; 9: 75[DOI][PubMed]
  • 30. Mokmeli S, Khazemikho N, Niromanesh S, Vatankhah Z. The application of low-level laser therapy after cesarean section does not compromise blood prolactin levels and lactation status. Photomed Laser Surg. 2009; 27(3): 509-12[DOI][PubMed]
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