Anesthesiology and Pain Medicine

Published by: Kowsar

Does Analgesic Effect of Opium Hamper the Adverse Effects of Severe Coronary Artery Disease on Quality of Life in Addicted Patients?

Mahdi Najafi 1 , * and Mehrdad Sheikhvatan 2
Authors Information
1 Anesthesiology Department, Tehran Heart Center, Tehran University of Medical Sciences (TUMS), Tehran, Iran
2 Research Department, Tehran Heart Center, Tehran University of Medical Sciences (TUMS), Tehran, Iran
Article information
  • Anesthesiology and Pain Medicine: June 21, 2012, 2 (1); 22-27
  • Published Online: July 10, 2012
  • Article Type: Research Article
  • Received: April 11, 2012
  • Revised: May 6, 2012
  • Accepted: May 8, 2012
  • DOI: 10.5812/aapm.5139

To Cite: Najafi M, Sheikhvatan M. Does Analgesic Effect of Opium Hamper the Adverse Effects of Severe Coronary Artery Disease on Quality of Life in Addicted Patients?, Anesth Pain Med. 2012 ; 2(1):22-27. doi: 10.5812/aapm.5139.

Copyright © 2012, Iranian Society of Regional Anesthesia and Pain Medicine (ISRAPM). This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License ( which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Background
2. Objectives
3. Patients and Methods
4. Results
5. Discussion
  • 1. Kalant H. Opium revisited: a brief review of its nature, composition, non-medical use and relative risks Addiction 1997; 92(3): 267-77
  • 2. United Nations Office on Drugs and Crime (UNDOC). World Drug Report 2009
  • 3. United Nations Office on Drugs and Crime (UNODC) field Office in Iran. Young people and drugs towards a comprehensive health promotion policy Tehran Report
  • 4. Sadeghian H, Sheikhvatan M, Mahmoodian M, Sheikhfathollahi M, Hakki E, Sadeghian A, et al. Comparison of Short-Term Clinical Outcome of Non-ST Elevation versus ST Elevation Myocardial Infarction J Tehran Heart Cent 2009; 4(2)
  • 5. Najafi M, Sheikhvatan M, Montazeri A. Quality of life-associated factors among patients undergoing coronary artery bypass surgery as measured using the WHOQOL-BREF Cardiovasc J Afr 2009; 20(5): 284-9
  • 6. Bernabei R, Gambassi G, Lapane K, Landi F, Gatsonis C, Dunlop R, et al. Management of pain in elderly patients with cancer. SAGE Study Group. Systematic Assessment of Geriatric Drug Use via Epidemiology JAMA 1998; 279(23): 1877-82
  • 7. Chou R, Fanciullo GJ, Fine PG, Adler JA, Ballantyne JC, Davies P, et al. Clinical guidelines for the use of chronic opioid therapy in chronic noncancer pain J Pain 2009; 10(2): 113-30
  • 8. Dunn KM, Saunders KW, Rutter CM, Banta-Green CJ, Merrill JO, Sullivan MD, et al. Opioid prescriptions for chronic pain and overdose: a cohort study Ann Intern Med 2010; 152(2): 85-92
  • 9. Bizzarri J, Rucci P, Vallotta A, Girelli M, Scandolari A, Zerbetto E, et al. Dual diagnosis and quality of life in patients in treatment for opioid dependence Subst Use Misuse 2005; 40(12): 1765-76
  • 10. Millson PE, Challacombe L, Villeneuve PJ, Fischer B, Strike CJ, Myers T, et al. Self-perceived health among Canadian opiate users: a comparison to the general population and to other chronic disease populations Can J Public Health 2004; 95(2): 99-103
  • 11. Smith KW, Larson MJ. Quality of life assessments by adult substance abusers receiving publicly funded treatment in Massachusetts Am J Drug Alcohol Abuse 2003; 29(2): 323-35
  • 12. Ware JE, Kosinski M, Bayliss MS, McHorney CA, Rogers WH, Raczek A. Comparison of methods for the scoring and statistical analysis of SF-36 health profile and summary measures: summary of results from the Medical Outcomes Study Med Care 1995; 33(4 Suppl)-79
  • 13. Mayer O, Simon J, Heidrich J, Cokkinos DV, De Bacquer D. Educational level and risk profile of cardiac patients in the EUROASPIRE II substudy J Epidemiol Community Health 2004; 58(1): 47-52
  • 14. Barrett-Connor E, Giardina EG, Gitt AK, Gudat U, Steinberg HO, Tschoepe D. Women and heart disease: the role of diabetes and hyperglycemia Arch Intern Med 2004; 164(9): 934-42
  • 15. VandenBos GR, A.P.A. . dictionary of psychology 2007;
  • 16. American Psychiatric Association . Diagnostic and statistical manual of mental disorders: DSM-IV-TR 2000;
  • 17. De Backer G, Ambrosioni E, Borch-Johnsen K, Brotons C, Cifkova R, Dallongeville J, et al. European guidelines on cardiovascular disease prevention in clinical practice: third joint task force of European and other societies on cardiovascular disease prevention in clinical practice (constituted by representatives of eight societies and by invited experts). Eur J Cardiovasc Prev Rehabil 2003; 10(4)
  • 18. Bartnik M, Ryden L, Ferrari R, Malmberg K, Pyorala K, Simoons M, et al. The prevalence of abnormal glucose regulation in patients with coronary artery disease across Europe. The Euro Heart Survey on diabetes and the heart Eur Heart J 2004; 25(21): 1880-90
  • 19. Chalmers J, MacMahon S, Mancia G, Whitworth J, Beilin L, Hansson L, et al. 1999 World Health Organization-International Society of Hypertension Guidelines for the management of hypertension. Guidelines sub-committee of the World Health Organization Clin Exp Hypertens 1999; 21(5–6): 1009-60
  • 20. American Diabetes Association . Diagnosis and classification of diabetes mellitus Diabetes Care 2008; 31: 55-60
  • 21. Scheuner MT, Whitworth WC, McGruder H, Yoon PW, Khoury MJ. Familial risk assessment for early-onset coronary heart disease Genet Med 2006; 8(8): 525-31
  • 22. Suwanwela C, Poshyachinda V, Tasanapradit P, Dharmkrong-At A. The hill tribes of Thailand, their opium use and addiction Bull Narc 1978; 30(2): 1-19
  • 23. Karam GA, Reisi M, Kaseb AA, Khaksari M, Mohammadi A, Mahmoodi M. Effects of opium addiction on some serum factors in addicts with non-insulin-dependent diabetes mellitus Addict Biol 2004; 9(1): 53-8
  • 24. Mohammadi A, Darabi M, Nasry M, Saabet-Jahromi MJ, Malek-Pour-Afshar R, Sheibani H. Effect of opium addiction on lipid profile and atherosclerosis formation in hypercholesterolemic rabbits Exp Toxicol Pathol 2009; 61(2): 145-9
  • 25. Sesso R, Yoshihiro MM. Time of diagnosis of chronic renal failure and assessment of quality of life in haemodialysis patients Nephrol Dial Transplant 1997; 12(10): 2111-6
  • 26. Meyer K, Laederach-Hofmann K. Effects of a comprehensive rehabilitation program on quality of life in patients with chronic heart failure Prog Cardiovasc Nurs 2003; 18(4): 169-76
  • 27. Metra M, Giubbini R, Nodari S, Boldi E, Modena MG, Dei Cas L. Differential effects of beta-blockers in patients with heart failure: A prospective, randomized, double-blind comparison of the long-term effects of metoprolol versus carvedilol Circulation 2000; 102(5): 546-51
  • 28. Liu Y, Yang YM, Zhu J, Tan HQ, Liang Y, Li JD. Prognostic significance of hemoglobin A1c level in patients hospitalized with coronary artery disease. A systematic review and meta-analysis Cardiovasc Diabetol 2011; 10: 98
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