Anesthesiology and Pain Medicine

Published by: Kowsar

Non-Trigger Anesthesia Management in a Patient With Leigh’s Syndrome Presenting for Dental Rehabilitation

M-Irfan Suleman 1 , * , Thejovathi Edala 2 , Edwin Abraham 1 and M-Saif Siddiqu 1
Authors Information
1 Division of Pediatric Anesthesia, Arkansas Children’s Hospital, Arkansas, USA
2 Department of Anesthesiology, University of Arkansas for Medical Sciences, Arkansas, USA
Article information
  • Anesthesiology and Pain Medicine: December 2015, 5 (6); e61537
  • Published Online: November 30, 2015
  • Article Type: Case Report
  • Received: July 21, 2015
  • Revised: August 27, 2015
  • Accepted: September 27, 2015
  • DOI: 10.5812/aapm.28804

To Cite: Suleman M, Edala T, Abraham E, Siddiqu M. Non-Trigger Anesthesia Management in a Patient With Leigh’s Syndrome Presenting for Dental Rehabilitation, Anesth Pain Med. 2015 ; 5(6):e61537. doi: 10.5812/aapm.28804.

Copyright © 2015, Iranian Society of Regional Anesthesia and Pain Medicine (ISRAPM).This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License ( which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Introduction
2. Case Presentation
  • 1. Leigh D. Subacute necrotizing encephalomyelopathy in an infant. J Neurol Neurosurg Psychiatry. 1951; 14(3): 216-21[PubMed]
  • 2. Thorburn DR, Rahman S. Mitochondrial DNA-associated Leigh Syndrome and NARP.
  • 3. Bains R, Moe MC, Larsen GA, Berg-Johnsen J, Vinje ML. Volatile anaesthetics depolarize neural mitochondria by inhibiton of the electron transport chain. Acta Anaesthesiol Scand. 2006; 50(5): 572-9[DOI][PubMed]
  • 4. Morgan PG, Hoppel CL, Sedensky MM. Mitochondrial defects and anesthetic sensitivity. Anesthesiology. 2002; 96(5): 1268-70[PubMed]
Creative Commons License Except where otherwise noted, this work is licensed under Creative Commons Attribution Non Commercial 4.0 International License .

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