Central Nervous System Toxicity After Botulinum Neurotoxin Injection
Anesthesiology and Pain Medicine: 3 (1); 223-5
June 30, 2013
Article Type: Case Report
November 28, 2012
January 13, 2013
R F, Knezevic
N N, Candido
K D. Central Nervous System Toxicity After Botulinum Neurotoxin Injection,
Anesth Pain Med.
Online ahead of Print
Since Its first description of botulism toxicity in 1820s, specific formulations of botulinum neurotoxin (BoNT) have been introduced with different clinical benefits. However, there is increasing number of adverse events reported to Food and Drug Administration. This report presents the case of 62-year-old woman with Parkinsons disease who received BoNT injections to treat painful spasticity in her hands. She developed severe generalized dystonia shortly after BoNT injections.
Botulinum Toxins, Type A; Parkinson Disease; Pain; Dystonic Disorders
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