Anesthesiology and Pain Medicine

Published by: Kowsar

An Evaluation of the Adding Magnesium Sulfate to Ropivacaine on Ultrasound-Guided Transverse Abdominis Plane Block After Abdominal Hysterectomy

Farnad Imani 1 , * , Poupak Rahimzadeh 1 , Hamid-Reza Faiz 2 and Alireza Abdullahzadeh-Baghaei 3
Authors Information
1 Pain Research Center, Iran University of Medical Sciences, Tehran, Iran
2 Anesthesiology Department, Iran University of Medical Sciences, Tehran, Iran
3 Anesthesiology, Critical Care and Pain Management Research Center, Hormozgan University of Medical Science, Bandarabbas, Iran
Article information
  • Anesthesiology and Pain Medicine: August 2018, 8 (4); e74124
  • Published Online: July 29, 2018
  • Article Type: Research Article
  • Received: April 30, 2018
  • Revised: June 10, 2018
  • Accepted: June 13, 2018
  • DOI: 10.5812/aapm.74124

To Cite: Imani F, Rahimzadeh P, Faiz H, Abdullahzadeh-Baghaei A. An Evaluation of the Adding Magnesium Sulfate to Ropivacaine on Ultrasound-Guided Transverse Abdominis Plane Block After Abdominal Hysterectomy, Anesth Pain Med. 2018 ; 8(4):e74124. doi: 10.5812/aapm.74124.

Copyright © 2018, Author(s). This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License ( which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited
1. Background
2. Objectives
3. Methods
4. Results
5. Discussion
  • 1. Farzi F, Naderi Nabi B, Mirmansouri A, Fakoor F, Atrkar Roshan Z, Biazar G, et al. Postoperative pain after abdominal hysterectomy: a randomized, double-blind, controlled trial comparing the effects of tramadol and gabapentin as premedication. Anesth Pain Med. 2016;6(1). e32360. doi: 10.5812/aapm.32360.
  • 2. Imani F, Rahimzadeh P. Gabapentinoids: gabapentin and pregabalin for postoperative pain management. Anesth Pain Med. 2012;2(2):52-3. doi: 10.5812/aapm.7743. [PubMed: 24223337]. [PubMed Central: PMC3821114].
  • 3. Imani F. Postoperative pain management. Anesth Pain Med. 2011;1(1):6-7. doi: 10.5812/aapm.1810.
  • 4. Imani F, Faiz HR, Sedaghat M, Hajiashrafi M. Effects of adding ketamine to fentanyl plus acetaminophen on postoperative pain by patient controlled analgesia in abdominal surgery. Anesth Pain Med. 2014;4. e12162.
  • 5. Vadivelu N, Mitra S, Narayan D. Recent advances in postoperative pain management. Yale J Biol Med. 2010;83(1):11-25. [PubMed: 20351978]. [PubMed Central: PMC2844689].
  • 6. Gupta A, Kaur K, Sharma S, Goyal S, Arora S, Murthy RS. Clinical aspects of acute post-operative pain management & its assessment. J Adv Pharm Technol Res. 2010;1:97-108.
  • 7. Taylor R, Pergolizzi JV, Sinclair A, Raffa RB, Aldington D, Plavin S, et al. Transversus abdominis block: clinical uses, side effects, and future perspectives. Pain Pract. 2013;13(4):332-44. doi: 10.1111/j.1533-2500.2012.00595.x.
  • 8. Ra YS, Kim CH, Lee GY, Han JL. The analgesic effect of the ultrasound-guided transverse abdominis plane block after laparoscopic cholecystectomy. Korean J Anesthesiol. 2010;58(4):362. doi: 10.4097/kjae.2010.58.4.362.
  • 9. Torup H, Bogeskov M, Hansen EG, Palle C, Rosenberg J, Mitchell AU, et al. Transversus abdominis plane (TAP) block after robot-assisted laparoscopic hysterectomy: a randomised clinical trial. Acta Anaesthesiol Scand. 2015;59(7):928-35. doi: 10.1111/aas.12516. [PubMed: 26032118].
  • 10. Onishi Y, Kato R, Okutomi T, Tabata K, Amano K, Unno N. Transversus abdominis plane block provides postoperative analgesic effects after cesarean section: Additional analgesia to epidural morphine alone. J Obstet Gynaecol Res. 2013;39(9):1397-405. doi: 10.1111/jog.12074.
  • 11. Telnes A, Skogvoll E, LonnEE H. Transversus abdominis plane block vs. wound infiltration in Caesarean section: a randomised controlled trial. Acta Anaesthesiol Scand. 2015;59(4):496-504. doi: 10.1111/aas.12498.
  • 12. Suresh S, Taylor LJ, De Oliveira GS, Lonnqvist PA. Dose effect of local anesthetics on analgesic outcomes for the transversus abdominis plane (TAP) block in children: a randomized, double-blinded, clinical trial. Paediatr Anaesth. 2015;25(5):506-10. doi: 10.1111/pan.12550.
  • 13. Pather S, Loadsman JA, Gopalan PD, Rao A, Philp S, Carter J. The role of transversus abdominis plane blocks in women undergoing total laparoscopic hysterectomy: a retrospective review. Aust N Z J Obstet Gynaecol. 2011;51(6):544-7. doi: 10.1111/j.1479-828X.2011.01369.x. [PubMed: 21923857].
  • 14. Gharaei H, Imani F, Almasi F, Solimani M. The effect of ultrasound-guided TAPB on pain management after total abdominal hysterectomy. Korean J Pain. 2013;26(4):374-8. doi: 10.3344/kjp.2013.26.4.374.
  • 15. Lee AR, Choe YS. Anesthesia experience for open gastrostomy with ultrasound-guided unilateral subcostal transversus abdominis plane block in a high risk elderly patient: a case report. Anesth Pain Med. 2015;5(3). e24890. doi: 10.5812/aapm.24890v2.
  • 16. Bjerregaard N, Nikolajsen L, Bendtsen TF, Rasmussen BS. Transversus abdominis plane catheter bolus analgesia after major abdominal surgery. Anesthesiol Res Pract. 2012;2012:1-5. doi: 10.1155/2012/596536.
  • 17. Kartalov A, Jankulovski N, Kuzmanovska B, Zdravkovska M, Shosholcheva M, Spirovska T, et al. Effect of adding dexamethasone as a ropivacaine adjuvant in ultrasound-guided transversus abdominis plane block for inguinal hernia repair. Pril (Makedon Akad Nauk Umet Odd Med Nauki). 2015;36(3):35-41. doi: 10.1515/prilozi-2015-0076.
  • 18. Niraj G, Kelkar A, Hart E, Horst C, Malik D, Yeow C, et al. Comparison of analgesic efficacy of four-quadrant transversus abdominis plane (TAP) block and continuous posterior TAP analgesia with epidural analgesia in patients undergoing laparoscopic colorectal surgery: an open-label, randomised, non-inferiority trial. Anaesthesia. 2014;69(4):348-55. doi: 10.1111/anae.12546.
  • 19. Dabbagh A, Elyasi H, Razavi SS, Fathi M, Rajaei S. Intravenous magnesium sulfate for post-operative pain in patients undergoing lower limb orthopedic surgery. Acta Anaesthesiol Scand. 2009;53(8):1088-91. doi: 10.1111/j.1399-6576.2009.02025.x.
  • 20. Xiao F, Xu W, Feng Y, Fu F, Zhang X, Zhang Y, et al. Intrathecal magnesium sulfate does not reduce the ED50 of intrathecal hyperbaric bupivacaine for cesarean delivery in healthy parturients: a prospective, double blinded, randomized dose-response trial using the sequential allocation method. BMC Anesthesiol. 2017;17(1):8. doi: 10.1186/s12871-017-0300-z.
  • 21. Mishriky BM, George RB, Habib AS. Transversus abdominis plane block for analgesia after Cesarean delivery: a systematic review and meta-analysis. Can J Anaesth. 2012;59(8):766-78. doi: 10.1007/s12630-012-9729-1.
  • 22. Mukhtar K. Transversus abdominis plane (TAP) block. JNY School Reg Anesth. 2009;12:28-33.
  • 23. Kiefer N, Krahe S, Gembruch U, Weber S. Ultrasound anatomy of the transversus abdominis plane region in pregnant women before and after cesarean delivery. BMC Anesthesiol. 2016;16(1):126. doi: 10.1186/s12871-016-0289-8. [PubMed: 28007030]. [PubMed Central: PMC5180404].
  • 24. Albrecht E, Kirkham KR, Liu SS, Brull R. Peri-operative intravenous administration of magnesium sulphate and postoperative pain: a meta-analysis. Anaesthesia. 2013;68(1):79-90. doi: 10.1111/j.1365-2044.2012.07335.x. [PubMed: 23121612].
  • 25. Young MJ, Gorlin AW, Modest VE, Quraishi SA. Clinical implications of the transversus abdominis plane block in adults. Anesthesiol Res Pract. 2012;2012:731645.
  • 26. McDonnell JG, Curley G, Carney J, Benton A, Costello J, Maharaj CH, et al. The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial. Anesth Analg. 2008;106(1):186-91. doi: 10.1213/01.ane.0000290294.64090.f3.
  • 27. Shin HJ, Kim ST, Yim KH, Lee HS, Sim JH, Shin YD. Preemptive analgesic efficacy of ultrasound-guided transversus abdominis plane block in patients undergoing gynecologic surgery via a transverse lower abdominal skin incision. Korean J Anesthesiol. 2011;61(5):413-8. doi: 10.4097/kjae.2011.61.5.413.
  • 28. Faiz SHR, Alebouyeh MR, Derakhshan P, Imani F, Rahimzadeh P, Ghaderi Ashtiani M. Comparison of ultrasound-guided posterior transversus abdominis plane block and lateral transversus abdominis plane block for postoperative pain management in patients undergoing cesarean section: a randomized double-blind clinical trial study. J Pain Res. 2018;11:5-9. doi: 10.2147/JPR.S146970. [PubMed: 29296094]. [PubMed Central: PMC5741073].
  • 29. Petersen PL, Hilsted KL, Dahl JB, Mathiesen O. Bilateral transversus abdominis plane (TAP) block with 24 hours ropivacaine infusion via TAP catheters: A randomized trial in healthy volunteers. BMC Anesthesiol. 2013;13(1):30. doi: 10.1186/1471-2253-13-30.
  • 30. Le-Wendling L, Ihnatsenka B, Haller A, Esch AT, Boezaart AP. The insiders' experiences with continuous transversus abdominis plane blocks for analgesia after cesarean delivery. Pain Med. 2013;14(2):305-8. doi: 10.1111/j.1526-4637.2012.01341.x.
  • 31. Heil JW, Nakanote KA, Madison SJ, Loland VJ, Mariano ER, Sandhu NS, et al. Continuous transversus abdominis plane (TAP) blocks for postoperative pain control after hernia surgery: a randomized, triple-masked, placebo-controlled study. Pain Med. 2014;15(11):1957-64. doi: 10.1111/pme.12530.
  • 32. Kim MG, Kim SI, Ok SY, Kim SH, Lee SJ, Park SY, et al. The analgesic effect of ultrasound-guided transverse abdominis plane block after laparoscopic totally extraperitoneal hernia repair. Korean J Anesthesiol. 2012;63(3):227-32. doi: 10.4097/kjae.2012.63.3.227. [PubMed: 23060979]. [PubMed Central: PMC3460151].
  • 33. Faiz SHR, Rahimzadeh P, Imani F, Bakhtiari A. Intrathecal injection of magnesium sulfate: shivering prevention during cesarean section: a randomized, double-blinded, controlled study. Korean J Anesthesiol. 2013;65(4):293. doi: 10.4097/kjae.2013.65.4.293.
  • 34. Haghighi M, Soleymanha M, Sedighinejad A, Mirbolook A, Naderi Nabi B, Rahmati M, et al. The effect of magnesium sulfate on motor and sensory axillary plexus blockade. Anesth Pain Med. 2015;5(1). e21943. doi: 10.5812/aapm.21943.
  • 35. Chin KJ, McDonnell JG, Carvalho B, Sharkey A, Pawa A, Gadsden J. Essentials of our current understanding. Regional Anesth Pain Med. 2017;42(2):133-83. doi: 10.1097/aap.0000000000000545.
  • 36. Rana S, Verma RK, Singh J, Chaudhary SK, Chandel A. Magnesium sulphate as an adjuvant to bupivacaine in ultrasound-guided transversus abdominis plane block in patients scheduled for total abdominal hysterectomy under subarachnoid block. Indian J Anaesth. 2016;60(3):174-9. doi: 10.4103/0019-5049.177879. [PubMed: 27053780]. [PubMed Central: PMC4800933].
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