Anesthesiology and Pain Medicine

Published by: Kowsar

Effect of Hypoxemia in the Determination of Short-Term Prognosis of Coronary Artery Bypass Graft Patients: A Prospective Study

Fardin Yousefshahi 1 , 2 , * , Elham Samadi 3 , Omalbanin Paknejad 4 , Ehsan Bastan Hagh 1 and Saber Aminzadeh 1
Authors Information
1 Department of Anesthesiology, Pain and Critical Care, Tehran University of Medical Sciences, Tehran, Iran
2 Brain and Spinal Cord Injury Research Center, Neuroscience Institute, Tehran University of Medical Sciences, Tehran, Iran
3 Kelvington Hospital, Kelvington, Saskatchewan, Canada
4 Department of Pulmonology, Tehran University of Medical Sciences, Tehran, Iran
Article information
  • Anesthesiology and Pain Medicine: 9 (1); e81785
  • Published Online: February 16, 2019
  • Article Type: Research Article
  • Received: July 6, 2018
  • Revised: November 7, 2018
  • Accepted: November 23, 2018
  • DOI: 10.5812/aapm.81785

To Cite: Yousefshahi F, Samadi E, Paknejad O , Bastan Hagh E, Aminzadeh S . Effect of Hypoxemia in the Determination of Short-Term Prognosis of Coronary Artery Bypass Graft Patients: A Prospective Study, Anesth Pain Med. Online ahead of Print ; 9(1):e81785. doi: 10.5812/aapm.81785.

Copyright © 2019, Author(s). This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License ( which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Background
2. Objectives
3. Methods
4. Results
5. Discussion
  • 1. Gupta V, Grover V. Risk assessment and outcome after CABG. Ann Card Anaesth. 2002;5(2):156-8. [PubMed: 17827606].
  • 2. Peterson ED, Coombs LP, Ferguson TB, Shroyer AL, DeLong ER, Grover FL, et al. Hospital variability in length of stay after coronary artery bypass surgery: Results from the Society of Thoracic Surgeon's National Cardiac Database. Ann Thorac Surg. 2002;74(2):464-73. doi: 10.1016/S0003-4975(02)03694-9. [PubMed: 12173830].
  • 3. Ferguson TB Jr, Hammill BG, Peterson ED, DeLong ER, Grover FL, S. T. S. National Database Committee . A decade of change-risk profiles and outcomes for isolated coronary artery bypass grafting procedures, 1990-1999: A report from the STS National Database Committee and the Duke Clinical Research Institute. Society of Thoracic Surgeons. Ann Thorac Surg. 2002;73(2):480-9. discussion 489-90. doi: 10.1016/S0003-4975(01)03339-2. [PubMed: 11845863].
  • 4. Tu JV, Sykora K, Naylor CD. Assessing the outcomes of coronary artery bypass graft surgery: How many risk factors are enough? Steering Committee of the Cardiac Care Network of Ontario. J Am Coll Cardiol. 1997;30(5):1317-23. doi: 10.1016/S0735-1097(97)00295-7. [PubMed: 9350934].
  • 5. Higgins TL, Estafanous FG, Loop FD, Beck GJ, Lee JC, Starr NJ, et al. ICU admission score for predicting morbidity and mortality risk after coronary artery bypass grafting. Ann Thorac Surg. 1997;64(4):1050-8. doi: 10.1016/S0003-4975(97)00553-5. [PubMed: 9354526].
  • 6. Chiarenza F, Tsoutsouras T, Cassisi C, Santonocito C, Gerry S, Astuto M, et al. The effects of on-pump and off-pump coronary artery bypass surgery on respiratory function in the early postoperative period. J Intensive Care Med. 2017:8.8506661769685E+14. doi: 10.1177/0885066617696852. [PubMed: 29112468].
  • 7. Cohen AJ, Katz MG, Frenkel G, Medalion B, Geva D, Schachner A. Morbid results of prolonged intubation after coronary artery bypass surgery. Chest. 2000;118(6):1724-31. doi: 10.1378/chest.118.6.1724. [PubMed: 11115465].
  • 8. Gluck EH. Predicting eventual success or failure to wean in patients receiving long-term mechanical ventilation. Chest. 1996;110(4):1018-24. doi: 10.1378/chest.110.4.1018. [PubMed: 8874263].
  • 9. Northrup WF 3rd, Emery RW, Nicoloff DM, Lillehei TJ, Holter AR, Blake DP. Opposite trends in coronary artery and valve surgery in a large multisurgeon practice, 1979-1999. Ann Thorac Surg. 2004;77(2):488-95. doi: 10.1016/S0003-4975(03)01359-6. [PubMed: 14759424].
  • 10. Ghotkar SV, Grayson AD, Fabri BM, Dihmis WC, Pullan DM. Preoperative calculation of risk for prolonged intensive care unit stay following coronary artery bypass grafting. J Cardiothorac Surg. 2006;1:14. doi: 10.1186/1749-8090-1-14. [PubMed: 16737548]. [PubMed Central: PMC1526720].
  • 11. Kaul TK, Fields BL, Riggins LS, Wyatt DA, Jones CR, Nagle D. Adult respiratory distress syndrome following cardiopulmonary bypass: Incidence, prophylaxis and management. J Cardiovasc Surg (Torino). 1998;39(6):777-81. [PubMed: 9972899].
  • 12. Bucerius J, Gummert JF, Walther T, Doll N, Falk V, Schmitt DV, et al. Predictors of prolonged ICU stay after on-pump versus off-pump coronary artery bypass grafting. Intensive Care Med. 2004;30(1):88-95. doi: 10.1007/s00134-003-1950-5. [PubMed: 14504725].
  • 13. Hsieh CH, Peng SK, Tsai TC, Shih YR, Peng SY. Prediction for major adverse outcomes in cardiac surgery: Comparison of three prediction models. J Formos Med Assoc. 2007;106(9):759-67. doi: 10.1016/S0929-6646(08)60037-6. [PubMed: 17908665].
  • 14. Salamonsen MR, Bailey MJ, Salamonsen RF. Can ICU stay be predicted accurately enough for fast-tracking cardiac surgical patients? Crit Care Resusc. 2008;10(3):194-201. [PubMed: 18798717].
  • 15. Rosenfeld R, Smith JM, Woods SE, Engel AM. Predictors and outcomes of extended intensive care unit length of stay in patients undergoing coronary artery bypass graft surgery. J Card Surg. 2006;21(2):146-50. doi: 10.1111/j.1540-8191.2006.00196.x. [PubMed: 16492273].
  • 16. Hein OV, Birnbaum J, Wernecke K, England M, Konertz W, Spies C. Prolonged intensive care unit stay in cardiac surgery: Risk factors and long-term-survival. Ann Thorac Surg. 2006;81(3):880-5. doi: 10.1016/j.athoracsur.2005.09.077. [PubMed: 16488688].
  • 17. Yousefshahi F, Bashirzadeh M, Abdollahi M, Mojtahedzadeh M, Salehiomran A, Jalali A, et al. Effect of hypertonic saline infusion versus normal saline on serum ngal and cystatin C levels in patients undergoing coronary artery bypass graft. J Tehran Heart Cent. 2013;8(1):21-7. [PubMed: 23646044]. [PubMed Central: PMC3587670].
  • 18. Mazandarani M, Yousefshahi F, Abdollahi M, Hamishehkar H, Barkhordari K, Boroomand MA, et al. Comparison of hypertonic saline versus normal saline on cytokine profile during CABG. Daru. 2012;20(1):49. doi: 10.1186/2008-2231-20-49. [PubMed: 23351427]. [PubMed Central: PMC3555740].
  • 19. Taggart DP. Respiratory dysfunction after cardiac surgery: Effects of avoiding cardiopulmonary bypass and the use of bilateral internal mammary arteries. Eur J Cardiothorac Surg. 2000;18(1):31-7. doi: 10.1016/S1010-7940(00)00438-3. [PubMed: 10869938].
  • 20. Royston D, Minty BD, Higenbottam TW, Wallwork J, Jones GJ. The effect of surgery with cardiopulmonary bypass on alveolar-capillary barrier function in human beings. Ann Thorac Surg. 1985;40(2):139-43. doi: 10.1016/S0003-4975(10)60006-9. [PubMed: 3896173].
  • 21. Haslam PL, Baker CS, Hughes DA, MacNaughton PD, Moat NE, Dewar A, et al. Pulmonary surfactant composition early in development of acute lung injury after cardiopulmonary bypass: Prophylactic use of surfactant therapy. Int J Exp Pathol. 1997;78(4):277-89. doi: 10.1046/j.1365-2613.1997.330364.x. [PubMed: 9505939]. [PubMed Central: PMC2694537].
  • 22. Wasowicz M, Sobczynski P, Biczysko W, Szulc R. Ultrastructural changes in the lung alveoli after cardiac surgical operations with the use of cardiopulmonary bypass (CPB). Pol J Pathol. 1999;50(3):189-96. [PubMed: 10624121].
  • 23. Vakili M, Shirani S, Paknejad O, Yousefshahi F. Acute respiratory distress syndrome diagnosis after coronary artery bypass: comparison between diagnostic criteria and clinical picture. Acta Med Iran. 2015;53(1):51-6. [PubMed: 25597606].
  • 24. Baghban M, Paknejad O, Yousefshahi F, Gohari Moghadam K, Bina P, Samimi Sadeh S. Hospital-acquired pneumonia in patients undergoing coronary artery bypass graft; comparison of the center for disease control clinical criteria with physicians' judgment. Anesth Pain Med. 2014;4(3). e20733. doi: 10.5812/aapm.20733. [PubMed: 25289379]. [PubMed Central: PMC4183076].
  • 25. Yousefshahi F, Barkhordari K, Movafegh A, Tavakoli V, Paknejad O, Bina P, et al. A New Method for Extubation: Comparison between Conventional and New Methods. J Tehran Heart Cent. 2012;7(3):121-7. [PubMed: 23304181]. [PubMed Central: PMC3524325].
  • 26. Kollef MH, Wragge T, Pasque C. Determinants of mortality and multiorgan dysfunction in cardiac surgery patients requiring prolonged mechanical ventilation. Chest. 1995;107(5):1395-401. doi: 10.1378/chest.107.5.1395. [PubMed: 7750337].
  • 27. Suematsu Y, Sato H, Ohtsuka T, Kotsuka Y, Araki S, Takamoto S. Predictive risk factors for pulmonary oxygen transfer in patients undergoing coronary artery bypass grafting. Jpn Heart J. 2001;42(2):143-53. doi: 10.1536/jhj.42.143. [PubMed: 11384075].
  • 28. Nozawa E, Azeka E, Ignez ZM, Feltrim Z, Auler Junior JO. Factors associated with failure of weaning from long-term mechanical ventilation after cardiac surgery. Int Heart J. 2005;46(5):819-31. doi: 10.1536/ihj.46.819. [PubMed: 16272773].
  • 29. Abrahamyan L, Demirchyan A, Thompson ME, Hovaguimian H. Determinants of morbidity and intensive care unit stay after coronary surgery. Asian Cardiovasc Thorac Ann. 2006;14(2):114-8. doi: 10.1177/021849230601400207. [PubMed: 16551817].
  • 30. Canver CC, Chanda J. Intraoperative and postoperative risk factors for respiratory failure after coronary bypass. Ann Thorac Surg. 2003;75(3):853-7. discussion 857-8. doi: 10.1016/S0003-4975(02)04493-4. [PubMed: 12645706].
  • 31. Weiss YG, Merin G, Koganov E, Ribo A, Oppenheim-Eden A, Medalion B, et al. Postcardiopulmonary bypass hypoxemia: A prospective study on incidence, risk factors, and clinical significance. J Cardiothorac Vasc Anesth. 2000;14(5):506-13. doi: 10.1053/jcan.2000.9488. [PubMed: 11052429].
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