Anesthesiology and Pain Medicine

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The Effect of Fibrinogen on Blood Loss After Lumbar Surgery: A Double-Blind Randomized Clinical Trial

Fatemeh Javaherforoosh Zadeh 1 , * , Farahzad Janatmakan 1 , Mohsen Shafaee Tonekaboni 1 and Mansoor Soltanzadeh 1
Authors Information
1 Department of Anesthesia, Ahvaz Anesthesiology and Pain Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
Article information
  • Anesthesiology and Pain Medicine: In Press (In Press); e91199
  • Published Online: June 1, 2019
  • Article Type: Research Article
  • Received: March 3, 2019
  • Revised: April 22, 2019
  • Accepted: April 26, 2019
  • DOI: 10.5812/aapm.91199

To Cite: Javaherforoosh Zadeh F, Janatmakan F, Shafaee Tonekaboni M, Soltanzadeh M. The Effect of Fibrinogen on Blood Loss After Lumbar Surgery: A Double-Blind Randomized Clinical Trial, Anesth Pain Med. Online ahead of Print ; In Press(In Press):e91199. doi: 10.5812/aapm.91199.

Abstract
Copyright © 2019, Author(s). This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Background
2. Objectives
3. Methods
4. Results
5. Discussion
Acknowledgements
Footnotes
References
  • 1. Wen L, Jin D, Xie W, Li Y, Chen W, Ding J, et al. Hidden blood loss in posterior lumbar fusion surgery: An analysis of risk factors. Clin Spine Surg. 2018;31(4):180-4. doi: 10.1097/BSD.0000000000000626. [PubMed: 29528878].
  • 2. Javaherforooshzadeh F, Monajemzadeh SA, Soltanzadeh M, Janatmakan F, Salari A, Saeed H. A comparative study of the amount of bleeding and hemodynamic changes between dexmedetomidine infusion and remifentanil infusion for controlled hypotensive anesthesia in lumbar discopathy surgery: A double-blind, randomized, clinical trial. Anesthesiol Pain Med. 2018;8(2). doi: 10.5812/aapm.66959.
  • 3. Irita K. [Present status of critical hemorrhage and its management in the operating room]. Rinsho Byori. 2014;62(12):1275-9. Japanese. [PubMed: 25823246].
  • 4. Yang L, Vuylsteke A, Gerrard C, Besser M, Baglin T. Postoperative fibrinogen level is associated with postoperative bleeding following cardiothoracic surgery and the effect of fibrinogen replacement therapy remains uncertain. J Thromb Haemost. 2013;11(8):1519-26. doi: 10.1111/jth.12304. [PubMed: 23710825].
  • 5. McQuilten ZK, Crighton G, Engelbrecht S, Gotmaker R, Brunskill SJ, Murphy MF, et al. Transfusion interventions in critical bleeding requiring massive transfusion: A systematic review. Transfus Med Rev. 2015;29(2):127-37. doi: 10.1016/j.tmrv.2015.01.001. [PubMed: 25716645].
  • 6. Kozek-Langenecker SA, Afshari A, Albaladejo P, Santullano CA, De Robertis E, Filipescu DC, et al. Management of severe perioperative bleeding: Guidelines from the European Society of Anaesthesiology. Eur J Anaesthesiol. 2013;30(6):270-382. doi: 10.1097/EJA.0b013e32835f4d5b. [PubMed: 23656742].
  • 7. Yuan L, Bao NR, Zhao JN. [Progress on hidden blood loss after hip replacement]. Zhongguo Gu Shang. 2015;28(4):378-82. Chinese. [PubMed: 26072626].
  • 8. Mu X, Wei J, Wang C, Ou Y, Yin D, Liang B, et al. Intravenous administration of tranexamic acid significantly reduces visible and hidden blood loss compared with its topical administration for double-segment posterior lumbar interbody fusion: A single-center, placebo-controlled, randomized trial. World Neurosurg. 2019;122:e821-7. doi: 10.1016/j.wneu.2018.10.154. [PubMed: 30391759].
  • 9. Ou Y, Wei J, Li R, Liang B, Qiu D, Wei M, et al. Clinical research of combined intravenous administration and topical application of tranexamic acid to a surgical wound during posterior lumbar fusion. Surg Innov. 2018;25(2):128-35. doi: 10.1177/1553350617751449. [PubMed: 29303065].
  • 10. Payani N, Foroughi M, Dabbagh A. The effect of intravenous administration of active recombinant factor vii on postoperative bleeding in cardiac valve reoperations; a randomized clinical trial. Anesth Pain Med. 2015;5(1). e22846. doi: 10.5812/aapm.22846. [PubMed: 25789239]. [PubMed Central: PMC4350162].
  • 11. Aawar N, Alikhan R, Bruynseels D, Cannings-John R, Collis R, Dick J, et al. Fibrinogen concentrate versus placebo for treatment of postpartum haemorrhage: study protocol for a randomised controlled trial. Trials. 2015;16:169. doi: 10.1186/s13063-015-0670-9. [PubMed: 25906770]. [PubMed Central: PMC4408576].
  • 12. Karlsson M, Ternstrom L, Hyllner M, Baghaei F, Skrtic S, Jeppsson A. Prophylactic fibrinogen infusion in cardiac surgery patients: Effects on biomarkers of coagulation, fibrinolysis, and platelet function. Clin Appl Thromb Hemost. 2011;17(4):396-404. doi: 10.1177/1076029610366437. [PubMed: 20530054].
  • 13. Karlsson M, Ternstrom L, Hyllner M, Baghaei F, Flinck A, Skrtic S, et al. Prophylactic fibrinogen infusion reduces bleeding after coronary artery bypass surgery. A prospective randomised pilot study. Thromb Haemost. 2009;102(1):137-44. doi: 10.1160/TH08-09-0587. [PubMed: 19572078].
  • 14. Shibata Y, Shigemi D, Ito M, Terada K, Nakanishi K, Kato M, et al. Association between fibrinogen levels and severity of postpartum hemorrhage in singleton vaginal deliveries at a Japanese perinatal center. J Nippon Med Sch. 2014;81(2):94-6. doi: 10.1272/jnms.81.94. [PubMed: 24805095].
  • 15. Hannon M, Quail J, Johnson M, Pugliese C, Chen K, Shorter H, et al. Fibrinogen and prothrombin complex concentrate in trauma coagulopathy. J Surg Res. 2015;196(2):368-72. doi: 10.1016/j.jss.2015.03.013. [PubMed: 25881790].
  • 16. Levy JH, Goodnough LT. How I use fibrinogen replacement therapy in acquired bleeding. Blood. 2015;125(9):1387-93. doi: 10.1182/blood-2014-08-552000. [PubMed: 25519751].
  • 17. Davenport R. Coagulopathy following major trauma hemorrhage: Lytic, lethal and a lack of fibrinogen. Crit Care. 2014;18(3):151. doi: 10.1186/cc13923. [PubMed: 25041819]. [PubMed Central: PMC4075417].
  • 18. De Lorenzo C, Calatzis A, Welsch U, Heindl B. Fibrinogen concentrate reverses dilutional coagulopathy induced in vitro by saline but not by hydroxyethyl starch 6%. Anesth Analg. 2006;102(4):1194-200. doi: 10.1213/01.ane.0000200297.98089.ce. [PubMed: 16551923].
  • 19. Hayakawa M, Sawamura A, Gando S, Kubota N, Uegaki S, Shimojima H, et al. Disseminated intravascular coagulation at an early phase of trauma is associated with consumption coagulopathy and excessive fibrinolysis both by plasmin and neutrophil elastase. Surgery. 2011;149(2):221-30. doi: 10.1016/j.surg.2010.06.010. [PubMed: 20655560].
  • 20. Martini WZ, Chinkes DL, Pusateri AE, Holcomb JB, Yu YM, Zhang XJ, et al. Acute changes in fibrinogen metabolism and coagulation after hemorrhage in pigs. Am J Physiol Endocrinol Metab. 2005;289(5):E930-4. doi: 10.1152/ajpendo.00137.2005. [PubMed: 15956050].
  • 21. Gerlach R, Raabe A, Zimmermann M, Siegemund A, Seifert V. Factor XIII deficiency and postoperative hemorrhage after neurosurgical procedures. Surg Neurol. 2000;54(3):260-4. discussion 264-5. doi: 10.1016/S0090-3019(00)00308-6. [PubMed: 11118574].
  • 22. Gerlach R, Tolle F, Raabe A, Zimmermann M, Siegemund A, Seifert V. Increased risk for postoperative hemorrhage after intracranial surgery in patients with decreased factor XIII activity: Implications of a prospective study. Stroke. 2002;33(6):1618-23. doi: 10.1161/01.STR.0000017219.83330.FF. [PubMed: 12053001].
  • 23. Sadeghi M, Atefyekta R, Azimaraghi O, Marashi SM, Aghajani Y, Ghadimi F, et al. A randomized, double blind trial of prophylactic fibrinogen to reduce bleeding in cardiac surgery. Braz J Anesthesiol. 2014;64(4):253-7. doi: 10.1016/j.bjane.2013.10.010. [PubMed: 24998109].
  • 24. Pournajafian A, Ghodraty M, Mohseni M, Ghamari AA, Sadeghi F. Reduction of intraoperative bleeding with fibrinogen administration in posterior spinal fusion surgery. J Isfahan Med School. 2015;33(347):1370-9.
  • 25. Ucar HI, Oc M, Tok M, Dogan OF, Oc B, Aydin A, et al. Preoperative fibrinogen levels as a predictor of postoperative bleeding after open heart surgery. Heart Surg Forum. 2007;10(5):E392-6. doi: 10.1532/HSF98.20071065. [PubMed: 17855205].
  • 26. Blome M, Isgro F, Kiessling AH, Skuras J, Haubelt H, Hellstern P, et al. Relationship between factor XIII activity, fibrinogen, haemostasis screening tests and postoperative bleeding in cardiopulmonary bypass surgery. Thromb Haemost. 2005;93(6):1101-7. doi: 10.1160/TH04-12-0799. [PubMed: 15968395].
  • 27. Thorarinsdottir HR, Sigurbjornsson FT, Hreinsson K, Onundarson PT, Gudbjartsson T, Sigurdsson GH. Effects of fibrinogen concentrate administration during severe hemorrhage. Acta Anaesthesiol Scand. 2010;54(9):1077-82. doi: 10.1111/j.1399-6576.2010.02289.x. [PubMed: 20887409].
  • 28. Carling MS, Jeppsson A, Wessberg P, Henriksson A, Baghaei F, Brisby H. Preoperative fibrinogen plasma concentration is associated with perioperative bleeding and transfusion requirements in scoliosis surgery. Spine (Phila Pa 1976). 2011;36(7):549-55. doi: 10.1097/BRS.0b013e3181d952dc. [PubMed: 21079540].
  • 29. Wafaisade A, Lefering R, Maegele M, Brockamp T, Mutschler M, Lendemans S, et al. Administration of fibrinogen concentrate in exsanguinating trauma patients is associated with improved survival at 6 hours but not at discharge. J Trauma Acute Care Surg. 2013;74(2):387-3. discussion 393-5. doi: 10.1097/TA.0b013e31827e2410. [PubMed: 23354229].
  • 30. Haas T, Spielmann N, Restin T, Seifert B, Henze G, Obwegeser J, et al. Higher fibrinogen concentrations for reduction of transfusion requirements during major paediatric surgery: A prospective randomised controlled trial. Br J Anaesth. 2015;115(2):234-43. doi: 10.1093/bja/aev136. [PubMed: 25982134].
  • 31. Geck MJ, Singh D, Gunn H, Stokes JK, Truumees E. Is preoperative fibrinogen testing associated with total blood loss in adolescent idiopathic scoliosis correction? Spine Deform. 2017;5(6):381-6. doi: 10.1016/j.jspd.2017.05.001. [PubMed: 29050713].
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