The Effect of EMLA Cream on Patient-Controlled Analgesia with Remifentanil in ESWL Procedure: A Placebo-Controlled Randomized Study

AUTHORS

Arzu Acar 1 , Elvan Erhan 1 , M. Nuri Deniz 1 , * , Gulden Ugur 1

1 Department of Anaesthesiology and Reanimation, School of Medicine, Ege University, [email protected], Turkey

How to Cite: Acar A, Erhan E, Nuri Deniz M, Ugur G. The Effect of EMLA Cream on Patient-Controlled Analgesia with Remifentanil in ESWL Procedure: A Placebo-Controlled Randomized Study, Anesth Pain Med. Online ahead of Print ; 2(3):119-122. doi: 10.5812/aapm.7790.

ARTICLE INFORMATION

Anesthesiology and Pain Medicine: 2 (3); 119-122
Published Online: January 1, 2013
Article Type: Research Article
Received: August 18, 2012
Accepted: October 10, 2012
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Abstract

Background: To alleviate stinging pain in the skin entry area and visceral discomfort in patients who are undergoing ESWL.

Objectives: This study was designed to investigate the effectiveness of the EMLA cream in combination with remifentanil patient-controlled analgesia (PCA) in patients undergoing ESWL treatment.

Patients and Methods: Sixty patients were divided into two double-blind randomized groups. Those in the first group were administered 3-5mm of EMLA 5% cream on a marked area; the second group received, as a placebo, a cream with no analgesic effect in the same amount. All patients were administered a remifentanil bolus with a PCA device. Arterial blood pressure, oxygen saturation, and respiratory rate were recorded throughout the procedure; postoperative side effects, agitation, and respiratory depression were measured after. Visual Analogue Scale (VAS) scores were taken preoperatively, perioperatively, directly postoperatively, and 60 minutes subsequent to finishing the procedure.

Results: There were no statistically significant differences in the frequency of PCA demands and delivered boluses or among perioperative VAS. No significant side effects were noted. Patient satisfaction was recorded high in both groups.

Conclusions: EMLA cream offered no advantage over the placebo cream in patients undergoing ESWL with remifentanil PCA.

Keywords

Lithotripsy Remifentanil Analgesia, Patient-Controlled EMLA

© 2013, Author(s). This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.

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